Dilantin and Mercaptopurine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dilantin (phenytoin sodium) and Mercaptopurine (mercaptopurine). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Dilantin and Mercaptopurine. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Dilantin?

Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,858 Dilantin users. Check the latest studies of Dilantin.

What is Mercaptopurine?

Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 23,013 Mercaptopurine users. Check the latest studies of Mercaptopurine.

On Jul, 16, 2026

14 people who take Dilantin and Mercaptopurine together, and have interactions are studied.

Dilantin and Mercaptopurine drug interactions.

What are the common drug interactions of Dilantin and Mercaptopurine, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Hypophagia (reduced food intake)
Coagulopathy (blood's ability to clot is impaired)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Drug ineffective
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Eating disorder
Emotional distress
Face oedema (swelling of face)

male:

n/a

What are the common drug interactions of Dilantin and Mercaptopurine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal distension
Abdominal pain
Coagulopathy (blood's ability to clot is impaired)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Emotional distress
Face oedema (swelling of face)
Haemorrhage intracranial (bleeding within the skull)
Hepatic failure (liver failure)
Injury

30-39:

Abdominal discomfort
Abnormal loss of weight
Activated partial thromboplastin time prolonged
Hepatic enzyme increased
Influenza
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

40-49:

n/a

50-59:

n/a

60+:

Acute lymphocytic leukaemia (cancer of the white blood cells)
Drug ineffective
General physical health deterioration (weak health status)
Hospitalisation
Hypophagia (reduced food intake)
Impaired healing
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Ulcer
Weight increased

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 7 people, 50.00%
Colitis (inflammation of colon): 7 people, 50.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 14.29%
Weight Loss: 1 person, 7.14%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 7.14%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 7.14%
Premenstrual Syndrome: 1 person, 7.14%
Pain: 1 person, 7.14%
Migraine (headache): 1 person, 7.14%
Inflammatory Bowel Disease: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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