Dilaudid and Biktarvy drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dilaudid (hydromorphone hydrochloride) and Biktarvy (bictegravir sodium; emtricitabine; tenofovir alafenamide fumarate). Common drug interactions include bone density decreased among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Dilaudid and Biktarvy. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Dilaudid?

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.

What is Biktarvy?

Biktarvy has active ingredients of bictegravir sodium; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 19,543 Biktarvy users. Check the latest studies of Biktarvy.



On Jul, 17, 2026

24 people who take Dilaudid and Biktarvy together, and have interactions are studied.

Dilaudid and Biktarvy drug interactions.

What are the common drug interactions of Dilaudid and Biktarvy, by gender? *:

female:

  1. Bone density decreased
  2. Bone loss
  3. Emotional distress
  4. Fracture
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  6. Osteonecrosis (death of bone)
  7. Osteoporosis (bones weak and more likely to break)

male:

  1. Emotional distress
  2. Chronic kidney disease
  3. Osteopenia (a condition where bone mineral density is lower than normal)
  4. Blood creatinine increased
  5. Fracture
  6. Hip arthroplasty
  7. Hypokalaemia (low potassium)
  8. Intervertebral disc degeneration (spinal disc degeneration)
  9. Lower limb fracture
  10. Upper limb fracture

What are the common drug interactions of Dilaudid and Biktarvy, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cryptococcosis (potentially fatal fungal disease)

30-39:

  1. Emotional distress
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Chronic kidney disease
  5. Bone density decreased
  6. Foot fracture
  7. Hand fracture
  8. Intervertebral disc degeneration (spinal disc degeneration)
  9. Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
  10. Tooth loss

40-49:

  1. Chronic kidney disease
  2. Bone density decreased
  3. Emotional distress
  4. Osteonecrosis (death of bone)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anxiety
  7. Hip arthroplasty
  8. Osteoporosis (bones weak and more likely to break)
  9. Fracture
  10. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

50-59:

  1. Bone density decreased
  2. Renal failure (kidney dysfunction)
  3. Chronic kidney disease
  4. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
  5. Hypokalaemia (low potassium)
  6. Osteoporosis (bones weak and more likely to break)
  7. Tooth loss
  8. Lower limb fracture
  9. Anaemia (lack of blood)
  10. Azotaemia (excess of urea or other nitrogenous compounds in the blood)

60+:

  1. Ankle fracture
  2. Bone density decreased
  3. Emotional distress
  4. Osteoporosis (bones weak and more likely to break)
  5. Tooth loss
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint)

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dilaudid and Biktarvy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dilaudid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Biktarvy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dilaudid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Biktarvy and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydromorphone hydrochloride and bictegravir sodium; emtricitabine; tenofovir alafenamide fumarate (the active ingredients of Dilaudid and Biktarvy, respectively), and Dilaudid and Biktarvy (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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