Dimetapp and Clonidine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dimetapp (brompheniramine maleate; phenylpropanolamine hydrochloride) and Clonidine (clonidine). Common drug interactions include cerebrovascular accident among females and haematocrit among males.
The phase IV clinical study analyzes what interactions people have when they take Dimetapp and Clonidine. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Dimetapp?
Dimetapp has active ingredients of brompheniramine maleate; phenylpropanolamine hydrochloride. It is often used in cough. eHealthMe is studying from 4,740 Dimetapp users. Check the latest studies of Dimetapp.
What is Clonidine?
Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.
12 people who take Dimetapp and Clonidine together, and have interactions are studied.

What are the common drug interactions of Dimetapp and Clonidine, by gender? *:
female:
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Pain
- Anxiety
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Injury
- Acidosis hyperchloraemic (increased acidity in the blood and other body tissue with decrease in plasma bicarbonate concentration)
- Anaemia (lack of blood)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Application site rash
male:
- Haematocrit
- Haemoglobin decreased
- Gait disturbance
- Nephrogenic anaemia (anaemia due to kidney disease)
- Nephropathy (damage to or disease of a kidney)
- Pain in extremity
- Renal failure (kidney dysfunction)
- Sinusitis (inflammation of sinus)
- Influenza
- Platelet count decreased
What are the common drug interactions of Dimetapp and Clonidine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Aggression
10-19:
n/a
20-29:
- Haematocrit
- Haemoglobin decreased
- Influenza
- Platelet count decreased
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Acidosis hyperchloraemic (increased acidity in the blood and other body tissue with decrease in plasma bicarbonate concentration)
- Anaemia (lack of blood)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Blood creatinine increased
30-39:
n/a
40-49:
- Pain in extremity
- Renal failure (kidney dysfunction)
- Back pain
- Chronic kidney disease
- Gait disturbance
- Nephrogenic anaemia (anaemia due to kidney disease)
- Nephropathy (damage to or disease of a kidney)
50-59:
- Pain
- Anxiety
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Injury
- Application site rash
60+:
n/a
What are the existing conditions these people have? *
- Pain: 2 people, 16.67%
- Breast Cancer: 2 people, 16.67%
- Nasopharyngitis (inflammation of the nasopharynx): 2 people, 16.67%
- Weight Decreased: 1 person, 8.33%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
- Cardiac Disorder: 1 person, 8.33%
- Depression: 1 person, 8.33%
- Eye Disorder: 1 person, 8.33%
- Eye Infection: 1 person, 8.33%
- Fever: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Dimetapp and Clonidine?
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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Dimetapp and Clonidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dimetapp:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clonidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dimetapp and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonidine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on brompheniramine maleate; phenylpropanolamine hydrochloride and clonidine (the active ingredients of Dimetapp and Clonidine, respectively), and Dimetapp and Clonidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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