Diovan hct and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diovan hct (hydrochlorothiazide; valsartan) and Premarin (estrogens, conjugated). Common drug interactions include chronic kidney disease among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Diovan hct and Premarin. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Diovan hct?

Diovan hct has active ingredients of hydrochlorothiazide; valsartan. It is often used in high blood pressure. eHealthMe is studying from 6,093 Diovan hct users. Check the latest studies of Diovan hct.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 26, 2026

57 people who take Diovan hct and Premarin together, and have interactions are studied.

Diovan hct and Premarin drug interactions.

What are the common drug interactions of Diovan Hct and Premarin, by gender? *:

female:

Chronic kidney disease
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)
Weight increased
Headache (pain in head)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Nephrogenic anaemia (anaemia due to kidney disease)
Pneumonia
Pruritus (severe itching of the skin)

male:

Arthralgia (joint pain)
Deafness
Hypersomnia (excessive daytime sleepiness (eds))
Joint stiffness
Peripheral swelling

What are the common drug interactions of Diovan Hct and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Ankylosing spondylitis (type of arthritis affecting the spine)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone disorder
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Device expulsion
Dislocation of vertebra
Exostosis (formation of new bone on the surface of a bone)
Intervertebral disc degeneration (spinal disc degeneration)
Multiple fractures
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

30-39:

Affective disorder (mental disorder)
Ankle fracture
Asthma
Breath sounds
Bronchial disorder
Bronchial haemorrhage (bleeding in bronchia)
Bronchial neoplasm (bronchial tumour)
Dyspnoea (difficult or laboured respiration)
Granuloma (a small area of inflammation due to tissue injury)
Herpes zoster

40-49:

Anxiety
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Overdose
Renal hypertension (high blood pressure caused by the kidneys hormonal response)

50-59:

Vertigo
Weight increased
Chronic kidney disease
Constipation
Diarrhoea
Drug ineffective
Influenza like illness
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)

60+:

Abdominal discomfort
Fall
Cystitis interstitial (unknown cause characterized by bladder pain)
Drug hypersensitivity
Dysuria (painful or difficult urination)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haemorrhage (bleeding)
Heart rate decreased
Implant site pain
Infusion site erythema (reddening of the skin at infusion site)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 26.32%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 12.28%
Osteoporosis (bones weak and more likely to break): 7 people, 12.28%
Abdominal Discomfort: 6 people, 10.53%
Asthma: 6 people, 10.53%
Depression: 6 people, 10.53%
Pain: 6 people, 10.53%
High Blood Cholesterol: 6 people, 10.53%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 8.77%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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