Diprivan and Ibuprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diprivan (propofol) and Ibuprofen (ibuprofen). Common drug interactions include bronchitis among females and scrotal swelling among males.

The phase IV clinical study analyzes what interactions people have when they take Diprivan and Ibuprofen. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

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eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

63 people who take Diprivan and Ibuprofen together, and have interactions are studied.

Diprivan and Ibuprofen drug interactions.

What are the common drug interactions of Diprivan and Ibuprofen, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cough
Depression
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Pain in extremity
Pneumonia

male:

Scrotal swelling
Anaemia (lack of blood)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Coronary artery stenosis (narrowing of coronary artery)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Dyslipidaemia (abnormal amount of lipids)
Eructation (release of gas from the digestive tract)
Exposed bone in jaw
Hunger

What are the common drug interactions of Diprivan and Ibuprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cerebral hypoperfusion (a condition in which the brain doesn't get enough blood)
Encephalitis (inflammation of the brain)
Hydrocephalus (water on the brain)
Hypokalaemia (low potassium)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Lipase increased
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal distension
Cerebral artery stenosis (hardening of brain blood vessels)
Delayed recovery from anaesthesia

10-19:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Abdominal abscess (collection of pus in abdomen)
Anastomotic leak
Ileal stenosis (obstruction in the ileal)
Pancreatitis (inflammation of pancreas)

20-29:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Anaesthetic complication
Delayed recovery from anaesthesia
Paralysis
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

30-39:

Injury
Breast enlargement
Menstruation irregular
Pelvic pain
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Acidosis (build-up of carbon dioxide in the blood)
Cavernous sinus thrombosis (formation of a blood clot in brain)
Cholecystitis chronic (long lasting infection of gallbladder)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

40-49:

Alcohol withdrawal syndrome
Fatigue (feeling of tiredness)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Loss of consciousness
Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
Anaphylactoid shock (serious allergic reaction that is rapid in onset and may cause death)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Breast cancer

50-59:

Gas gangrene (bacterial infection that produces gas within tissues)
Genital abscess (build up of pus in genital)
Groin abscess (pus in groin)
Groin pain
Hypotension (abnormally low blood pressure)
Scrotal cyst (cyst of scrotum)
Scrotal pain
Sepsis (a severe blood infection that can lead to organ failure and death)
Testicular pain (pain in testes)
Tumour associated fever (fever because of tumour)

60+:

Anxiety
Asthenia (weakness)
Presyncope
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Abdominal pain
Aortic valve incompetence
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Cholecystitis (infection of gallbladder)

What are the existing conditions these people have? *

Type 2 Diabetes: 9 people, 14.29%
Weight Decreased: 8 people, 12.70%
Hypotension (abnormally low blood pressure): 8 people, 12.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 11.11%
Sedation: 6 people, 9.52%
Nausea (feeling of having an urge to vomit): 6 people, 9.52%
Hypersensitivity: 6 people, 9.52%
High Blood Pressure: 6 people, 9.52%
Anaesthesia: 6 people, 9.52%
Depression: 5 people, 7.94%

* Approximation only. Some reports may have incomplete information.

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