Dofetilide and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dofetilide (dofetilide) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include liver disorder among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Dofetilide and Hydroxyzine. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Dofetilide?

Dofetilide has active ingredients of dofetilide. eHealthMe is studying from 2,646 Dofetilide users. Check the latest studies of Dofetilide.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.



On Jul, 26, 2026

15 people who take Dofetilide and Hydroxyzine together, and have interactions are studied.

Dofetilide and Hydroxyzine drug interactions.

What are the common drug interactions of Dofetilide and Hydroxyzine, by gender? *:

female:

  1. Liver disorder (liver diseases)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Chest pain
  4. Constipation
  5. Drug hypersensitivity
  6. Drug ineffective
  7. Muscle spasms (muscle contraction)
  8. Nausea (feeling of having an urge to vomit)
  9. Osteopenia (a condition where bone mineral density is lower than normal)
  10. Pneumonia

male:

  1. Abdominal discomfort
  2. Asthenia (weakness)
  3. Hospitalisation
  4. Loss of control of legs
  5. Muscular weakness (muscle weakness)
  6. Nausea (feeling of having an urge to vomit)
  7. Rigors (an episode of shaking or exaggerated shivering)
  8. Scar
  9. Vomiting
  10. Wound haemorrhage (bleeding wound)

What are the common drug interactions of Dofetilide and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Drug hypersensitivity

50-59:

n/a

60+:

  1. Vomiting
  2. Asthenia (weakness)
  3. Muscle spasms (muscle contraction)
  4. Muscular weakness (muscle weakness)
  5. Osteopenia (a condition where bone mineral density is lower than normal)
  6. Rash
  7. Rigors (an episode of shaking or exaggerated shivering)
  8. Scar
  9. Urticaria (rash of round, red welts on the skin that itch intensely)
  10. Visual acuity reduced (reduced clearness of vision)

What are the existing conditions these people have? *

  1. Parkinson's Disease: 3 people, 20.00%
  2. Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 13.33%
  3. Multiple Myeloma (cancer of the plasma cells): 1 person, 6.67%
  4. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 6.67%
  5. Dermatitis Allergic (inflammation of the skin due allergic reaction): 1 person, 6.67%
  6. Breast Cancer Female: 1 person, 6.67%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Dofetilide and Hydroxyzine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dofetilide and Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dofetilide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dofetilide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyzine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dofetilide and hydroxyzine hydrochloride (the active ingredients of Dofetilide and Hydroxyzine, respectively), and Dofetilide and Hydroxyzine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: