Donepezil and Bydureon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Donepezil (donepezil hydrochloride) and Bydureon (exenatide synthetic). Common drug interactions include decreased appetite among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Donepezil and Bydureon. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Donepezil?

Donepezil has active ingredients of donepezil hydrochloride. It is often used in dementia. eHealthMe is studying from 24,564 Donepezil users. Check the latest studies of Donepezil.

What is Bydureon?

Bydureon has active ingredients of exenatide synthetic. It is often used in type 2 diabetes. eHealthMe is studying from 24,309 Bydureon users. Check the latest studies of Bydureon.

On Jul, 23, 2026

27 people who take Donepezil and Bydureon together, and have interactions are studied.

Donepezil and Bydureon drug interactions.

What are the common drug interactions of Donepezil and Bydureon, by gender? *:

female:

Decreased appetite
Fatigue (feeling of tiredness)
Asthenia (weakness)
Blood glucose increased
Weight decreased
Body height decreased
Pneumonia
Abdominal discomfort
Abdominal wall mass
Acute myocardial infarction (acute heart attack)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Stent placement
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Dry skin
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrointestinal mucosal disorder (disorder of gastrointestinal lining mucous membranes)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Donepezil and Bydureon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Acute myocardial infarction (acute heart attack)
Balance disorder
Diarrhoea
Dizziness
Drug ineffective
Gait disturbance
Hypertension (high blood pressure)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Decreased appetite
Chronic kidney disease
Hepatic lesion
Hydronephrosis (water inside the kidney)
Knee arthroplasty
Pancreatic carcinoma (pancreatic cancer)
Pancreatitis (inflammation of pancreas)
Parkinson's disease
Stent placement
Abdominal discomfort

What are the existing conditions these people have? *

High Blood Cholesterol: 10 people, 37.04%
Diabetes: 8 people, 29.63%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 25.93%
Depression: 7 people, 25.93%
High Blood Pressure: 6 people, 22.22%
Memory Loss: 5 people, 18.52%
Pain: 3 people, 11.11%
Hypersensitivity: 3 people, 11.11%
Chest Pain: 3 people, 11.11%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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