Doxepin hydrochloride and Doxycycline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxepin hydrochloride (doxepin hydrochloride) and Doxycycline (doxycycline hyclate). Common drug interactions include tinnitus among females and amnesia among males.

The phase IV clinical study analyzes what interactions people have when they take Doxepin hydrochloride and Doxycycline. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Doxepin hydrochloride?

Doxepin hydrochloride has active ingredients of doxepin hydrochloride. It is often used in insomnia. eHealthMe is studying from 2,323 Doxepin hydrochloride users. Check the latest studies of Doxepin hydrochloride.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,866 Doxycycline users. Check the latest studies of Doxycycline.

On Jul, 20, 2026

18 people who take Doxepin hydrochloride and Doxycycline together, and have interactions are studied.

Doxepin hydrochloride and Doxycycline drug interactions.

What are the common drug interactions of Doxepin Hydrochloride and Doxycycline, by gender? *:

female:

Tinnitus (a ringing in the ears)
Type 2 diabetes mellitus
Visual disturbance
Nausea (feeling of having an urge to vomit)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Chest pain
Chronic kidney disease
Dehydration (dryness resulting from the removal of water)

male:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anger
Post-traumatic stress disorder
Sedation
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Multiple drug overdose intentional
Suicide attempt
Asperger's disorder (autism spectrum disorder that affects language and behavioural development in children)
Coeliac disease (simple food intolerance)

What are the common drug interactions of Doxepin Hydrochloride and Doxycycline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chest discomfort
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Malaise (a feeling of general discomfort or uneasiness)

30-39:

Conjunctivitis (pink eye)
Dry eye (lack of adequate tears)
Multiple drug overdose intentional
Ocular rosacea (redness, irritation or burning of the eyes)
Suicide attempt

40-49:

Nausea (feeling of having an urge to vomit)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anger
Asperger's disorder (autism spectrum disorder that affects language and behavioural development in children)
Coeliac disease (simple food intolerance)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Constipation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diarrhoea

50-59:

Nausea (feeling of having an urge to vomit)
Rash
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Abdominal pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Metastatic neoplasm (spreadable cancer tumour)
Ovarian cancer (cancer of ovary)
Paralysis
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Swelling face
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Asthenia (weakness)

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 16.67%
Nausea (feeling of having an urge to vomit): 3 people, 16.67%
Asthma: 3 people, 16.67%
Depression: 3 people, 16.67%
Pain: 2 people, 11.11%
Anaemia (lack of blood): 2 people, 11.11%
Infection: 2 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.11%
High Blood Pressure: 2 people, 11.11%
Cardiac Disorder: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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