Doxycycline and Fungizone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Fungizone (amphotericin b). Common drug interactions include renal failure acute among females and acarodermatitis among males.
The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Fungizone. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Doxycycline?
Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,866 Doxycycline users. Check the latest studies of Doxycycline.
What is Fungizone?
Fungizone has active ingredients of amphotericin b. eHealthMe is studying from 4,456 Fungizone users. Check the latest studies of Fungizone.
17 people who take Doxycycline and Fungizone together, and have interactions are studied.

What are the common drug interactions of Doxycycline and Fungizone, by gender? *:
female:
- Renal failure acute (rapid kidney dysfunction)
- Blood creatine phosphokinase increased
- Mixed liver injury
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Asthenia (weakness)
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
male:
- Acarodermatitis (skin inflammation caused by mites (acarids))
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Urinary retention (the inability to completely or partially empty the bladder)
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Pruritus (severe itching of the skin)
- Nerve compression
- Neuropathy peripheral (surface nerve damage)
- Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
What are the common drug interactions of Doxycycline and Fungizone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Renal failure acute (rapid kidney dysfunction)
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Asthenia (weakness)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Emotional distress
- General physical health deterioration (weak health status)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Injury
40-49:
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Pemphigoid (tense blisters on the skin)
- Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
- Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
- Urinary retention (the inability to completely or partially empty the bladder)
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Pruritus (severe itching of the skin)
- Nerve compression
- Neuropathy peripheral (surface nerve damage)
50-59:
n/a
60+:
- Blood creatine phosphokinase increased
- Mixed liver injury
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Liver disorder (liver diseases)
What are the existing conditions these people have? *
- Lung Neoplasm Malignant (cancer tumour of lung): 8 people, 47.06%
- Itching: 8 people, 47.06%
- Pelvic Inflammatory Disease: 3 people, 17.65%
- Oropharyngeal Candidiasis (fungal infection of oropharynx): 3 people, 17.65%
- Vaginal Yeast Infection: 3 people, 17.65%
- Anorectal Disorder: 3 people, 17.65%
- Rashes (redness): 3 people, 17.65%
- Oral Candidiasis (fungal infection of mouth): 2 people, 11.76%
- Device Related Infection: 2 people, 11.76%
- Lung Disorder (lung disease): 2 people, 11.76%
* Approximation only. Some reports may have incomplete information.
Do you take Doxycycline and Fungizone?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Doxycycline (60,866 reports)
- Fungizone (4,456 reports)
Browse all drug interactions of Doxycycline and Fungizone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Doxycycline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Fungizone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Doxycycline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fungizone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on doxycycline hyclate and amphotericin b (the active ingredients of Doxycycline and Fungizone, respectively), and Doxycycline and Fungizone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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