Doxycycline and Normodyne drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Normodyne (labetalol hydrochloride). Common drug interactions include acute respiratory failure among females and cellulitis of male external genital organ among males.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Normodyne. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

What is Normodyne?

Normodyne has active ingredients of labetalol hydrochloride. eHealthMe is studying from 858 Normodyne users. Check the latest studies of Normodyne.



On Aug, 01, 2026

16 people who take Doxycycline and Normodyne together, and have interactions are studied.

Doxycycline and Normodyne drug interactions.

What are the common drug interactions of Doxycycline and Normodyne, by gender? *:

female:

  1. Acute respiratory failure
  2. Candida sepsis (candida in blood stream)
  3. Anaemia (lack of blood)
  4. Hypoxia (low oxygen in tissues)
  5. Rectal haemorrhage (bleeding from anus)
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Chest pain
  9. Cluster headache (one-sided head pain with tearing)
  10. Diarrhoea

male:

  1. Cellulitis of male external genital organ (infection of male genitals soft tissue)
  2. Gastric dysplasia (stomach with abnormality of development)
  3. Dry mouth
  4. Dysuria (painful or difficult urination)
  5. Eye pain
  6. Flushing (the warm, red condition of human skin)
  7. Genital abscess (build up of pus in genital)
  8. Glaucoma (increased fluid pressure in the eye with vision loss)
  9. Groin abscess (pus in groin)
  10. Laryngeal neoplasm (tumour of larynx)

What are the common drug interactions of Doxycycline and Normodyne, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Postpartum haemorrhage (bleeding in woman after she has given birth)

30-39:

n/a

40-49:

n/a

50-59:

  1. Anaemia (lack of blood)
  2. Hypoxia (low oxygen in tissues)
  3. Rectal haemorrhage (bleeding from anus)
  4. Cellulitis of male external genital organ (infection of male genitals soft tissue)
  5. Scrotal abscess (pus in scrotum)
  6. Scrotal swelling
  7. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Cellulitis (infection under the skin)
  10. Chest pain

60+:

  1. Anal abscess
  2. Cellulitis of male external genital organ (infection of male genitals soft tissue)
  3. Genital abscess (build up of pus in genital)
  4. Groin abscess (pus in groin)
  5. Perineal abscess
  6. Scrotal abscess (pus in scrotum)
  7. Scrotal infection (infection in scrotum area)
  8. Staphylococcal infection (an infection with staphylococcus bacteria)

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 37.50%
  2. Hypotension (abnormally low blood pressure): 6 people, 37.50%
  3. High Blood Pressure: 5 people, 31.25%
  4. Nausea (feeling of having an urge to vomit): 4 people, 25.00%
  5. Sleep Disorder: 4 people, 25.00%
  6. Depression: 4 people, 25.00%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 25.00%
  8. Breast Infection: 3 people, 18.75%
  9. Constipation: 3 people, 18.75%
  10. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Doxycycline and Normodyne:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Normodyne:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Doxycycline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Normodyne and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate and labetalol hydrochloride (the active ingredients of Doxycycline and Normodyne, respectively), and Doxycycline and Normodyne (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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