Dramamine and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dramamine (dimenhydrinate) and Acetaminophen (acetaminophen). Common drug interactions include decreased appetite among females and influenza among males.

The phase IV clinical study analyzes what interactions people have when they take Dramamine and Acetaminophen. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Dramamine?

Dramamine has active ingredients of dimenhydrinate. It is often used in motion sickness. eHealthMe is studying from 1,386 Dramamine users. Check the latest studies of Dramamine.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 02, 2026

42 people who take Dramamine and Acetaminophen together, and have interactions are studied.

Dramamine and Acetaminophen drug interactions.

What are the common drug interactions of Dramamine and Acetaminophen, by gender? *:

female:

Decreased appetite
Fatigue (feeling of tiredness)
Influenza
Nausea (feeling of having an urge to vomit)
Vomiting
Weight decreased
Asthenia (weakness)
Malaise (a feeling of general discomfort or uneasiness)
Hypertension (high blood pressure)
Pain in extremity

male:

Influenza
Aspartate aminotransferase increased
Overdose
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Weight decreased
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Anxiety
Cerebellar ataxia (loss of coordination)
Emotional distress

What are the common drug interactions of Dramamine and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

Cardiac murmur (an heart sound in valve abnormality)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Hypercapnia (too much smoke)
Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Influenza

40-49:

Ankylosing spondylitis (type of arthritis affecting the spine)
Drug ineffective
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Inflammatory bowel disease
Infusion related reaction
Lactose intolerance (inability to digest lactose)
Loss of consciousness
Memory impairment
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

50-59:

Influenza
Blood potassium decreased
Cerebellar ataxia (loss of coordination)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gait disturbance
Hypersensitivity
Muscle spasms (muscle contraction)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)

60+:

Decreased appetite
Fatigue (feeling of tiredness)
Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)
Blood cholesterol increased
Body temperature increased
Bone pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Confusional state

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 10 people, 23.81%
Depression: 8 people, 19.05%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 11.90%
Immunodeficiency Common Variable: 5 people, 11.90%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.52%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 7.14%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 7.14%
Nausea (feeling of having an urge to vomit): 3 people, 7.14%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 7.14%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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