Dtic-dome and Dexamethasone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dtic-dome (dacarbazine) and Dexamethasone (dexamethasone). Common drug interactions include abdominal pain among females and pulmonary embolism among males.

The phase IV clinical study analyzes what interactions people have when they take Dtic-dome and Dexamethasone. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Dtic-dome?

Dtic-dome has active ingredients of dacarbazine. eHealthMe is studying from 206 Dtic-dome users. Check the latest studies of Dtic-dome.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.

On Jul, 21, 2026

19 people who take Dtic-dome and Dexamethasone together, and have interactions are studied.

Dtic-dome and Dexamethasone drug interactions.

What are the common drug interactions of Dtic-Dome and Dexamethasone, by gender? *:

female:

Abdominal pain
Acute circulatory failure (shock)
Anuria (failure of the kidneys to produce urine)
Ascites (accumulation of fluid in the abdominal cavity)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Nausea (feeling of having an urge to vomit)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls)

male:

Pulmonary embolism (blockage of the main artery of the lung)
Activated partial thromboplastin time prolonged
Disease progression
Drug effect decreased
Drug toxicity
Dyspnoea (difficult or laboured respiration)
Hypercoagulation (increased tendency for clotting of the blood)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypoxia (low oxygen in tissues)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Dtic-Dome and Dexamethasone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Dyspnoea (difficult or laboured respiration)

20-29:

n/a

30-39:

Blood pressure decreased
Drug hypersensitivity
Erythema (redness of the skin)
Flushing (the warm, red condition of human skin)
Hypersensitivity
Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

Drug effect decreased
Vomiting

50-59:

Activated partial thromboplastin time prolonged
Fibrin d dimer increased
Abdominal pain
Acute circulatory failure (shock)
Anuria (failure of the kidneys to produce urine)
Ascites (accumulation of fluid in the abdominal cavity)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Malignant neoplasm progression (cancer tumour came back)
Metastatic malignant melanoma (spreadable cancer tumour of melanine)

60+:

Clamminess (moist, sticky, and cold to the touch)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Nausea (feeling of having an urge to vomit)
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory distress (difficulty in breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sweating increased (excess sweating)
Vomiting

What are the existing conditions these people have? *

Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 3 people, 15.79%
Hodgkin's Lymphoma (cancer originating from white blood cells): 3 people, 15.79%
Malignant Melanoma (skin cancer rises from melancytes): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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