Duac and Lamictal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duac (benzoyl peroxide; clindamycin phosphate) and Lamictal (lamotrigine). Common drug interactions include asthenia among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Duac and Lamictal. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Duac?

Duac has active ingredients of benzoyl peroxide; clindamycin phosphate. It is often used in acne. eHealthMe is studying from 745 Duac users. Check the latest studies of Duac.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,626 Lamictal users. Check the latest studies of Lamictal.

On Jul, 20, 2026

19 people who take Duac and Lamictal together, and have interactions are studied.

What are the common drug interactions of Duac and Lamictal, by gender? *:

female:

Asthenia (weakness)
Blood glucose increased
Dry eye (lack of adequate tears)
Dry mouth
Eye pain
Fatigue (feeling of tiredness)
Feeding disorder (when children refuse to eat certain food groups)
Headache (pain in head)
Pain
Photophobia (extreme sensitivity to light)

male:

Confusional state
Anxiety
Fatigue (feeling of tiredness)
Hypoaldosteronism (decreased levels of the hormone aldosterone)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Renal failure (kidney dysfunction)
Somnambulism (sleep walking)
Blood pressure increased
Hypersensitivity
Respiration (transport of oxygen from the outside air to the cells within tissues)

What are the common drug interactions of Duac and Lamictal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Rash
Stress

30-39:

Asthenia (weakness)
Blood glucose increased
Dry eye (lack of adequate tears)
Dry mouth
Eye pain
Fatigue (feeling of tiredness)
Feeding disorder (when children refuse to eat certain food groups)
Headache (pain in head)
Pain
Photophobia (extreme sensitivity to light)

40-49:

Aspartate aminotransferase increased
Confusional state
Disturbance in attention
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hyperhidrosis (abnormally increased sweating)
Hypermetabolism (abnormal increase in the body's basal metabolic rate)
Night sweats (sweating in night)
Petit mal epilepsy (absence seizure)
Blood pressure increased
Essential hypertension (primary hypertension)

50-59:

Behcet's syndrome (involves inflammation of the blood vessels)
Blood cortisol decreased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Immune system disorder
Mouth ulceration (mouth ulcers)
Oesophageal candidiasis (fungal infection of oesophagus)
Sinusitis (inflammation of sinus)
Tinnitus (a ringing in the ears)
Ulcer

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 78.95%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 3 people, 15.79%
Pituitary Tumor Benign: 3 people, 15.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
Asthma: 1 person, 5.26%
Behcet's Syndrome (involves inflammation of the blood vessels): 1 person, 5.26%
Blood Cortisol Abnormal: 1 person, 5.26%
Cerebral Disorder (brain disease): 1 person, 5.26%
Diabetes: 1 person, 5.26%
Dry Eyes (lack of adequate tears): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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