Duoneb and Primidone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duoneb (albuterol sulfate; ipratropium bromide) and Primidone (primidone). Common drug interactions include dry mouth among females and loss of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Duoneb and Primidone. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Duoneb?

Duoneb has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 8,093 Duoneb users. Check the latest studies of Duoneb.

What is Primidone?

Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.



On Jul, 11, 2026

48 people who take Duoneb and Primidone together, and have interactions are studied.

Duoneb and Primidone drug interactions.

What are the common drug interactions of Duoneb and Primidone, by gender? *:

female:

  1. Dry mouth
  2. Dry skin
  3. Eye abscess
  4. Faecal incontinence (a lack of control over passing stool)
  5. Fall
  6. Fatigue (feeling of tiredness)
  7. Flatulence (flatus expelled through the anus)
  8. Gait disturbance
  9. Glaucoma (increased fluid pressure in the eye with vision loss)
  10. Haemolytic anaemia (anaemia due to haemolysis)

male:

  1. Loss of consciousness
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Pneumonia
  4. Death
  5. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  6. Respiratory tract infection
  7. Hypertension (high blood pressure)
  8. Allergy to plants
  9. Hypersensitivity
  10. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Duoneb and Primidone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  4. Rales (an abnormal respiratory sound characterized by fine crackles)
  5. Respiration (transport of oxygen from the outside air to the cells within tissues)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Stent placement
  8. Suicidal ideation
  9. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  10. Urinary tract infection

50-59:

  1. Anxiety
  2. Atelectasis (partial or complete collapse of the lung)
  3. Bacteraemia (presence of bacteria in the blood)
  4. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  5. Lethargy (tiredness)
  6. Leukocytosis (increased white blood cells)
  7. Lymphoma (cancer that begins in immune system cells)
  8. Nervousness
  9. Oxygen saturation decreased
  10. Pancreatic carcinoma (pancreatic cancer)

60+:

  1. Pneumonia
  2. Blood creatinine increased
  3. Pruritus (severe itching of the skin)
  4. Respiratory distress (difficulty in breathing)
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Respiratory tract infection
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Urinary tract infection
  9. Abdominal pain
  10. Acute respiratory failure

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 29.17%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 27.08%
  3. Pain: 11 people, 22.92%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 16.67%
  5. Hypersensitivity: 7 people, 14.58%
  6. Urinary Tract Infection: 6 people, 12.50%
  7. Osteoporosis (bones weak and more likely to break): 6 people, 12.50%
  8. High Blood Cholesterol: 6 people, 12.50%
  9. Sleep Disorder: 5 people, 10.42%
  10. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 5 people, 10.42%

* Approximation only. Some reports may have incomplete information.

Do you take Duoneb and Primidone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Duoneb and Primidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Duoneb:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Primidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duoneb and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Primidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide and primidone (the active ingredients of Duoneb and Primidone, respectively), and Duoneb and Primidone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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