Dupixent and Kalydeco drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dupixent (dupilumab) and Kalydeco (ivacaftor). Common drug interactions include infective pulmonary exacerbation of cystic fibrosis among females.
The phase IV clinical study analyzes what interactions people have when they take Dupixent and Kalydeco. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Dupixent?
Dupixent has active ingredients of dupilumab. eHealthMe is studying from 257,631 Dupixent users. Check the latest studies of Dupixent.
What is Kalydeco?
Kalydeco has active ingredients of ivacaftor. eHealthMe is studying from 6,652 Kalydeco users. Check the latest studies of Kalydeco.
11 people who take Dupixent and Kalydeco together, and have interactions are studied.
What are the common drug interactions of Dupixent and Kalydeco, by gender? *:
female:
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Cough
- Infection
- Cystic fibrosis (disease of the secretary glands)
- Asthma
- Constipation
- Dyspnoea (difficult or laboured respiration)
male:
n/a
What are the common drug interactions of Dupixent and Kalydeco, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Cough
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Asthma
- Constipation
- Dyspnoea (difficult or laboured respiration)
What are the existing conditions these people have? *
- Asthma: 8 people, 72.73%
- Cystic Fibrosis (disease of the secretary glands): 7 people, 63.64%
- Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 27.27%
- Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Dupixent and Kalydeco?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Dupixent and Kalydeco:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dupixent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Kalydeco:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dupixent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Kalydeco and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on dupilumab and ivacaftor (the active ingredients of Dupixent and Kalydeco, respectively), and Dupixent and Kalydeco (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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