Duricef and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duricef (cefadroxil/cefadroxil hemihydrate) and Flonase (fluticasone propionate). Common drug interactions include pneumonia staphylococcal among females and actinic keratosis among males.

The phase IV clinical study analyzes what interactions people have when they take Duricef and Flonase. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Duricef?

Duricef has active ingredients of cefadroxil/cefadroxil hemihydrate. eHealthMe is studying from 579 Duricef users. Check the latest studies of Duricef.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.



On Aug, 08, 2026

17 people who take Duricef and Flonase together, and have interactions are studied.

Duricef and Flonase drug interactions.

What are the common drug interactions of Duricef and Flonase, by gender? *:

female:

  1. Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
  2. Pruritus (severe itching of the skin)
  3. Renal failure acute (rapid kidney dysfunction)
  4. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  5. Road traffic accident
  6. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  7. Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle)
  8. Sinus bradycardia (an unusually slow heartbeat due to heart disease)
  9. Skin lesion
  10. Surgery

male:

  1. Actinic keratosis (skin disease due to sun exposure)
  2. Adenoma benign (non-cancerous tumour -secreting)
  3. Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
  4. Neuropathy peripheral (surface nerve damage)
  5. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Polyp
  8. Rectal haemorrhage (bleeding from anus)
  9. Telangiectasia (small dilated blood vessels near the surface of the skin)
  10. Anaemia (lack of blood)

What are the common drug interactions of Duricef and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal distension
  2. Anaemia postoperative
  3. Angina pectoris (chest pain due to ischemia of the heart muscle)
  4. Cerebral infarction (less blood supply to brain resulting tissue damage)
  5. Cerebrovascular disorder (disease of brain)
  6. Chest pain
  7. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Drug ineffective
  10. Eyelid ptosis (falling of the upper or lower eyelid)

50-59:

  1. Anasarca (general swelling, or massive oedema)
  2. Arthralgia (joint pain)
  3. Aspartate aminotransferase increased
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  7. Chest tightness
  8. Cough
  9. Gamma-glutamyltransferase increased
  10. Hypoaesthesia (reduced sense of touch or sensation)

60+:

  1. Anaemia (lack of blood)
  2. Cellulitis (infection under the skin)
  3. Injection site haemorrhage (bleeding from injection site)
  4. Periorbital oedema (swelling around the eyes)
  5. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  6. Platelet count decreased
  7. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 5 people, 29.41%
  2. Pain: 5 people, 29.41%
  3. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 23.53%
  4. Affective Disorder (mental disorder): 3 people, 17.65%
  5. High Blood Pressure: 2 people, 11.76%
  6. Seasonal Allergy (allergic condition due to certain season): 2 people, 11.76%
  7. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 11.76%
  8. Depression: 2 people, 11.76%
  9. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 11.76%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Duricef and Flonase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Duricef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flonase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duricef and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flonase and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cefadroxil/cefadroxil hemihydrate and fluticasone propionate (the active ingredients of Duricef and Flonase, respectively), and Duricef and Flonase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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