Dynacirc and Hydrochlorothiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dynacirc (isradipine) and Hydrochlorothiazide (hydrochlorothiazide). Common drug interactions include renal failure chronic among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Dynacirc and Hydrochlorothiazide. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Dynacirc?

Dynacirc has active ingredients of isradipine. eHealthMe is studying from 975 Dynacirc users. Check the latest studies of Dynacirc.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,195 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

91 people who take Dynacirc and Hydrochlorothiazide together, and have interactions are studied.

Dynacirc and Hydrochlorothiazide drug interactions.

What are the common drug interactions of Dynacirc and Hydrochlorothiazide, by gender? *:

female:

Renal failure chronic (long lasting kidney dysfunction)
Oedema peripheral (superficial swelling)
Anaemia (lack of blood)
Abdominal pain
Anxiety
Vomiting
Cardiac failure congestive
Renal failure acute (rapid kidney dysfunction)
Diarrhoea
Abdominal pain upper

male:

Blood creatinine increased
Renal failure acute (rapid kidney dysfunction)
Fall
Fatigue (feeling of tiredness)
Syncope (loss of consciousness with an inability to maintain postural tone)
Death
Decreased appetite
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Gait disturbance

What are the common drug interactions of Dynacirc and Hydrochlorothiazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abnormal weight gain
Adverse reaction
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cataract (clouding of the lens inside the eye)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Contusion (a type of hematoma of tissue in which capillaries)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Device expulsion
Drug intolerance (drug sensitivity)

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gastrointestinal pain
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Pain in extremity
Vomiting

50-59:

Multiple injuries
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Visual acuity reduced (reduced clearness of vision)
Headache (pain in head)
Cardiac failure congestive
Acidosis (build-up of carbon dioxide in the blood)
Cataract cortical (it affects outer part of lens)
Impaired work ability
Iron deficiency anaemia

60+:

Asthenia (weakness)
Nausea (feeling of having an urge to vomit)
Bone pain
Decreased appetite
Fall
Gait disturbance
Pneumonia
Abdominal discomfort
Dysuria (painful or difficult urination)
Pain

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 12 people, 13.19%
High Blood Cholesterol: 7 people, 7.69%
Pain: 6 people, 6.59%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 5.49%

* Approximation only. Some reports may have incomplete information.

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