Eligard and Benicar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eligard (leuprolide acetate) and Benicar (olmesartan medoxomil). Common drug interactions include asthenia among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Eligard and Benicar. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Eligard?

Eligard has active ingredients of leuprolide acetate. It is often used in prostate cancer. eHealthMe is studying from 44,652 Eligard users. Check the latest studies of Eligard.

What is Benicar?

Benicar has active ingredients of olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 36,002 Benicar users. Check the latest studies of Benicar.



On Jul, 13, 2026

29 people who take Eligard and Benicar together, and have interactions are studied.

Eligard and Benicar drug interactions.

What are the common drug interactions of Eligard and Benicar, by gender? *:

female:

  1. Asthenia (weakness)
  2. Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
  3. Atrioventricular block first degree (heart block first degree)
  4. Back pain
  5. Balance disorder
  6. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  7. Blood albumin decreased
  8. Blood glucose decreased
  9. Blood pressure fluctuation
  10. Blood urea increased

male:

  1. Agitation (state of anxiety or nervous excitement)
  2. Back pain
  3. Blood pressure fluctuation
  4. Bone disorder
  5. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  6. Constipation
  7. Deafness
  8. Decreased interest
  9. Fatigue (feeling of tiredness)
  10. General physical health deterioration (weak health status)

What are the common drug interactions of Eligard and Benicar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Hypocalcaemia (levels of calcium in blood serum are abnormally low)

60+:

  1. Agitation (state of anxiety or nervous excitement)
  2. Back pain
  3. Blood pressure fluctuation
  4. Bone disorder
  5. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  6. Constipation
  7. Deafness
  8. Decreased interest
  9. Fatigue (feeling of tiredness)
  10. General physical health deterioration (weak health status)

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 14 people, 48.28%
  2. Asthma: 3 people, 10.34%
  3. Arrhythmias (irregular heartbeat): 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

Do you take Eligard and Benicar?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Eligard and Benicar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Eligard:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Benicar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Eligard and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Benicar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on leuprolide acetate and olmesartan medoxomil (the active ingredients of Eligard and Benicar, respectively), and Eligard and Benicar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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