Emend and Zevalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emend (aprepitant) and Zevalin (ibritumomab tiuxetan). Common drug interactions include cholestasis among females and pancytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Emend and Zevalin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Emend?

Emend has active ingredients of aprepitant. It is often used in nausea. eHealthMe is studying from 13,741 Emend users. Check the latest studies of Emend.

What is Zevalin?

Zevalin has active ingredients of ibritumomab tiuxetan. eHealthMe is studying from 2,258 Zevalin users. Check the latest studies of Zevalin.



On Jul, 08, 2026

16 people who take Emend and Zevalin together, and have interactions are studied.

Emend and Zevalin drug interactions.

What are the common drug interactions of Emend and Zevalin, by gender? *:

female:

  1. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  2. Diarrhoea
  3. Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
  4. Generalised oedema (swelling all over the body)
  5. Stomatitis (inflammation of mucous membrane of mouth)
  6. Transaminases increased
  7. Venoocclusive disease (small veins in the liver are obstructed)
  8. Vomiting
  9. Fluid retention (an abnormal accumulation of fluid in the blood)
  10. Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)

male:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  3. Cardiac disorder
  4. Clostridial infection (infectious conditions by clostridium bacteria)
  5. Device related infection
  6. Hyperthermia (body temperature greatly above normal)
  7. Oxygen saturation decreased
  8. Pyrexia (fever)
  9. Stem cell transplant
  10. Aspergillosis (an infection caused by a fungus called aspergillus)

What are the common drug interactions of Emend and Zevalin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Device related infection
  2. Febrile neutropenia (fever with reduced white blood cells)

40-49:

n/a

50-59:

  1. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  2. Diarrhoea
  3. Escherichia infection (bacterial infection by escherichia coli)
  4. Hepatosplenomegaly (enlargement of both the liver and the spleen)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Aplasia (defective development or congenital absence of an organ or tissue)
  7. Culture stool positive
  8. Febrile neutropenia (fever with reduced white blood cells)
  9. Respiratory syncytial virus infection (viral disease of respiratory system)
  10. Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)

60+:

n/a

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 25.00%
  2. Nausea And Vomiting: 4 people, 25.00%
  3. Bone Marrow Conditioning Regimen: 3 people, 18.75%
  4. Nodal Marginal Zone B-Cell Lymphoma (a type of blood cancer occurs within the lymph nodes): 2 people, 12.50%
  5. Fever: 2 people, 12.50%
  6. Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 12.50%
  7. Mucosal Inflammation (infection of mucous membrane): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Emend and Zevalin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Emend and Zevalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Emend:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zevalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Emend and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zevalin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on aprepitant and ibritumomab tiuxetan (the active ingredients of Emend and Zevalin, respectively), and Emend and Zevalin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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