Emla and Methylphenidate hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emla (lidocaine; prilocaine) and Methylphenidate hydrochloride (methylphenidate hydrochloride). Common drug interactions include renal impairment among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Emla and Methylphenidate hydrochloride. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Emla?

Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.

What is Methylphenidate hydrochloride?

Methylphenidate hydrochloride has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 6,822 Methylphenidate hydrochloride users. Check the latest studies of Methylphenidate hydrochloride.

On Jul, 09, 2026

11 people who take Emla and Methylphenidate hydrochloride together, and have interactions are studied.

Emla and Methylphenidate hydrochloride drug interactions.

What are the common drug interactions of Emla and Methylphenidate Hydrochloride, by gender? *:

female:

Renal impairment (severely reduced kidney function)
Tooth disorder (tooth disease)
Urinary tract infection
Arthralgia (joint pain)
Colitis (inflammation of colon)
Hypotension (abnormally low blood pressure)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pruritus (severe itching of the skin)

male:

Death
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Endocarditis (inflammation in heart muscle)
Overdose

What are the common drug interactions of Emla and Methylphenidate Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Endocarditis (inflammation in heart muscle)

10-19:

n/a

20-29:

Overdose

30-39:

n/a

40-49:

n/a

50-59:

Colitis (inflammation of colon)
Hypotension (abnormally low blood pressure)

60+:

Death
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 54.55%
Pain: 6 people, 54.55%
Fatigue (feeling of tiredness): 5 people, 45.45%
Insomnia (sleeplessness): 2 people, 18.18%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 18.18%
Cellulitis (infection under the skin): 2 people, 18.18%
Cough: 2 people, 18.18%
Depression: 2 people, 18.18%
Diarrhea: 2 people, 18.18%
Sedation: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Emla and Methylphenidate hydrochloride?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously