Entresto and Ceftriaxone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Entresto (sacubitril; valsartan) and Ceftriaxone (ceftriaxone sodium). Common drug interactions include sepsis among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Entresto and Ceftriaxone. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Entresto?

Entresto has active ingredients of sacubitril; valsartan. eHealthMe is studying from 126,628 Entresto users. Check the latest studies of Entresto.

What is Ceftriaxone?

Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.

On Aug, 10, 2026

51 people who take Entresto and Ceftriaxone together, and have interactions are studied.

Entresto and Ceftriaxone drug interactions.

What are the common drug interactions of Entresto and Ceftriaxone, by gender? *:

female:

Sepsis (a severe blood infection that can lead to organ failure and death)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Asthenia (weakness)
Blood lactic acid increased
Clostridium test positive
Diarrhoea
Lethargy (tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Pain in extremity

male:

Dyspnoea (difficult or laboured respiration)
Abdominal distension
Cardiac failure congestive
Cough
Head injury
Loss of consciousness
Cardiac failure
Haematemesis (vomiting of blood)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the common drug interactions of Entresto and Ceftriaxone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Dyspnoea (difficult or laboured respiration)
Abdominal distension
Pneumonia
Cardiac failure congestive
Head injury
Loss of consciousness
Cardiac failure
Haematemesis (vomiting of blood)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the existing conditions these people have? *

Cardiac Failure: 18 people, 35.29%
Parkinson's Disease: 5 people, 9.80%
Pain: 5 people, 9.80%
Lung Disorder (lung disease): 5 people, 9.80%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 5 people, 9.80%
Anaemia (lack of blood): 5 people, 9.80%
Diabetes: 4 people, 7.84%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 7.84%
Infection: 3 people, 5.88%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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