Epitol and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Epitol (carbamazepine) and Simvastatin (simvastatin). Common drug interactions include arthralgia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Epitol and Simvastatin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Epitol?

Epitol has active ingredients of carbamazepine. It is often used in bipolar disorder. eHealthMe is studying from 397 Epitol users. Check the latest studies of Epitol.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.



On Jul, 30, 2026

15 people who take Epitol and Simvastatin together, and have interactions are studied.

Epitol and Simvastatin drug interactions.

What are the common drug interactions of Epitol and Simvastatin, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Chondropathy (disease of the cartilage)
  4. Chronic kidney disease
  5. Crying
  6. Depression
  7. Facial bones fracture (bone fracture of face)
  8. Hyperhidrosis (abnormally increased sweating)
  9. Joint crepitation
  10. Memory impairment

male:

  1. Pain
  2. Back pain
  3. Pulmonary infarction (death of a small area of lung)
  4. Decreased appetite
  5. Adverse drug reaction
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Back disorder
  8. Cough
  9. Dyspnoea (difficult or laboured respiration)
  10. Fall

What are the common drug interactions of Epitol and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Adverse drug reaction
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Arthralgia (joint pain)
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Chondropathy (disease of the cartilage)
  6. Cough
  7. Drug ineffective
  8. Dyspnoea (difficult or laboured respiration)
  9. Facial bones fracture (bone fracture of face)
  10. Fall

60+:

  1. Back pain
  2. Chills (felling of cold)
  3. Decreased appetite
  4. Back disorder
  5. Chronic kidney disease
  6. Drug ineffective
  7. Injection site extravasation (flow of (blood or lymph) from injection site)
  8. Joint injury
  9. Limb discomfort (discomfort in leg)
  10. Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 26.67%
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 20.00%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 13.33%
  4. Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 2 people, 13.33%
  5. Gait Disturbance: 2 people, 13.33%
  6. Depression: 2 people, 13.33%
  7. High Blood Pressure: 2 people, 13.33%
  8. Thyroid Diseases: 2 people, 13.33%
  9. Birth Control: 1 person, 6.67%
  10. Balance Disorder: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Epitol and Simvastatin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Epitol and Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Epitol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Epitol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simvastatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on carbamazepine and simvastatin (the active ingredients of Epitol and Simvastatin, respectively), and Epitol and Simvastatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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