Erleada and Xtandi drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Erleada (apalutamide) and Xtandi (enzalutamide). Common drug interactions include rash among males.
The phase IV clinical study analyzes what interactions people have when they take Erleada and Xtandi. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.
What is Erleada?
Erleada has active ingredients of apalutamide. eHealthMe is studying from 7,519 Erleada users. Check the latest studies of Erleada.
What is Xtandi?
Xtandi has active ingredients of enzalutamide. eHealthMe is studying from 51,498 Xtandi users. Check the latest studies of Xtandi.
72 people who take Erleada and Xtandi together, and have interactions are studied.
What are the common drug interactions of Erleada and Xtandi, by gender? *:
female:
n/a
male:
- Rash
- Fatigue (feeling of tiredness)
- Prostatic specific antigen increased
- Arthralgia (joint pain)
- Back pain
- Chondropathy (disease of the cartilage)
- Constipation
- Neutropenia (an abnormally low number of neutrophils)
- Vision blurred
- White blood cell count decreased
What are the common drug interactions of Erleada and Xtandi, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Neuropathy peripheral (surface nerve damage)
- Platelet count decreased
- Subdural haematoma (blood collects between the skull and the surface of the brain)
60+:
- Rash
- Hot flush (sudden feelings of heat)
- Interstitial lung disease
- Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
- Diarrhoea
- Dry skin
- Erythema (redness of the skin)
- Muscle spasms (muscle contraction)
- Prostatic specific antigen increased
- Death
What are the existing conditions these people have? *
- Prostate Cancer: 49 people, 68.06%
- Prostate Cancer Metastatic: 9 people, 12.50%
- High Blood Pressure: 4 people, 5.56%
- Depression: 4 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Erleada and Xtandi?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Erleada and Xtandi:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Erleada:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xtandi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Erleada and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xtandi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on apalutamide and enzalutamide (the active ingredients of Erleada and Xtandi, respectively), and Erleada and Xtandi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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