Eskalith and Cogentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eskalith (lithium carbonate) and Cogentin (benztropine mesylate). Common drug interactions include lipase increased among females and mania among males.

The phase IV clinical study analyzes what interactions people have when they take Eskalith and Cogentin. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Eskalith?

Eskalith has active ingredients of lithium carbonate. eHealthMe is studying from 1,448 Eskalith users. Check the latest studies of Eskalith.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

On Jul, 16, 2026

55 people who take Eskalith and Cogentin together, and have interactions are studied.

Eskalith and Cogentin drug interactions.

What are the common drug interactions of Eskalith and Cogentin, by gender? *:

female:

Lipase increased
Nasopharyngitis (inflammation of the nasopharynx)
Obesity (having too much body fat)
Overdose
Restless legs syndrome (a powerful urge to move your legs)
Sinus headache (headache caused by sinus infections)
Suicide attempt
Syncope (loss of consciousness with an inability to maintain postural tone)
Thrombocythaemia (an increased number of platelets in the circulating blood)
Pancreatitis acute (sudden inflammation of pancreas)

male:

Mania (a state of abnormally elevated or irritable mood)
Libido decreased (loss of interest in sex)
Thirst
Vomiting
Periodontal disease (disease that attacks the gum and bone and around the teeth)
Psychotic disorder
Drug level increased
Drug level decreased
Visual disturbance
Drug ineffective

What are the common drug interactions of Eskalith and Cogentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Ataxia (loss of full control of bodily movements)
Blood creatine phosphokinase increased
Blood in stool
Cough
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic coma
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diarrhoea
Emotional disorder
Gynaecomastia (enlargement of the gland tissue of the male breast)

20-29:

Abdominal pain
Acute sinusitis
Adjustment disorder with mixed anxiety and depressed mood
Aggression
Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
Asthenia (weakness)
Back pain
Bipolar disorder (mood disorder)
Borderline personality disorder
Chest pain

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug abuse
Dysphagia (a condition in which swallowing is difficult or painful)
Electrocardiogram abnormal
Electrocardiogram qt prolonged
Hot flush (sudden feelings of heat)
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

40-49:

Depression
Libido decreased (loss of interest in sex)
Mania (a state of abnormally elevated or irritable mood)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Dysgeusia (disorder of the sense of taste)
Psychotic disorder
Somnolence (a state of near-sleep, a strong desire for sleep)
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Dry mouth

50-59:

Cardiac disorder
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Diabetic coma
Drooling (drop saliva uncontrollably from the mouth)
Drug ineffective
Dysarthria (speech disorder)
Electrocardiogram st segment elevation
Electrocardiogram t wave peaked
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Headache (pain in head)

60+:

Psychotic disorder

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 13 people, 23.64%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 11 people, 20.00%
Bipolar Disorder (mood disorder): 8 people, 14.55%
Psychotic Disorder: 5 people, 9.09%
Sleep Disorder: 3 people, 5.45%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 3 people, 5.45%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 5.45%
Insomnia (sleeplessness): 3 people, 5.45%
Affective Disorder (mental disorder): 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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