Etodolac and Pioglitazone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Etodolac (etodolac) and Pioglitazone (pioglitazone hydrochloride). Common drug interactions include fall among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Etodolac and Pioglitazone. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Etodolac?

Etodolac has active ingredients of etodolac. It is often used in arthritis. eHealthMe is studying from 9,157 Etodolac users. Check the latest studies of Etodolac.

What is Pioglitazone?

Pioglitazone has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 12,864 Pioglitazone users. Check the latest studies of Pioglitazone.



On Jul, 15, 2026

45 people who take Etodolac and Pioglitazone together, and have interactions are studied.

Etodolac and Pioglitazone drug interactions.

What are the common drug interactions of Etodolac and Pioglitazone, by gender? *:

female:

  1. Fall
  2. Back pain
  3. Fractured sacrum
  4. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  5. Arthralgia (joint pain)
  6. Pubis fracture
  7. Cancer pain
  8. Decreased appetite
  9. Gastroenteritis (inflammation of stomach and intestine)
  10. Pulmonary embolism (blockage of the main artery of the lung)

male:

  1. Chronic kidney disease
  2. Asthenia (weakness)
  3. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Anxiety
  6. Cardiac arrest
  7. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  8. Emotional distress
  9. Headache (pain in head)
  10. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

What are the common drug interactions of Etodolac and Pioglitazone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anxiety
  2. Chronic kidney disease
  3. Dizziness
  4. Emotional distress
  5. Fatigue (feeling of tiredness)
  6. Nephrolithiasis (calculi in the kidneys)
  7. Renal impairment (severely reduced kidney function)

50-59:

  1. Chronic kidney disease
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Depression
  5. Emotional distress
  6. Pulmonary embolism (blockage of the main artery of the lung)
  7. Anal abscess
  8. Coma (state of unconsciousness lasting more than six hours)
  9. Gangrene (body tissue dies)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

  1. Fall
  2. Back pain
  3. Cerebral haemorrhage (bleeding within the brain)
  4. Epistaxis (bleed from the nose)
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Leukocytosis (increased white blood cells)
  8. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  9. Thrombocytopenia (decrease of platelets in blood)
  10. Cardiac arrest

What are the existing conditions these people have? *

  1. Pain: 5 people, 11.11%
  2. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 8.89%
  3. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 8.89%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.67%
  5. Hiv Infection: 3 people, 6.67%
  6. High Blood Pressure: 3 people, 6.67%
  7. High Blood Cholesterol: 3 people, 6.67%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Etodolac and Pioglitazone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Etodolac and Pioglitazone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Etodolac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pioglitazone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Etodolac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pioglitazone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on etodolac and pioglitazone hydrochloride (the active ingredients of Etodolac and Pioglitazone, respectively), and Etodolac and Pioglitazone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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