Evoxac and Lansoprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Evoxac (cevimeline hydrochloride) and Lansoprazole (lansoprazole). Common drug interactions include toxic epidermal necrolysis among females and back injury among males.

The phase IV clinical study analyzes what interactions people have when they take Evoxac and Lansoprazole. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Evoxac?

Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.

What is Lansoprazole?

Lansoprazole has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 129,663 Lansoprazole users. Check the latest studies of Lansoprazole.

On Jul, 13, 2026

38 people who take Evoxac and Lansoprazole together, and have interactions are studied.

Evoxac and Lansoprazole drug interactions.

What are the common drug interactions of Evoxac and Lansoprazole, by gender? *:

female:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Ulnar nerve palsy
Urinary tract infection
Urine output decreased
Palpitations (feelings or sensations that your heart is pounding or racing)
Dyspnoea (difficult or laboured respiration)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Cardiomegaly (increased size of heart than normal)
Arthralgia (joint pain)
Iron deficiency anaemia

male:

Back injury
Anaemia (lack of blood)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pyrexia (fever)
Viral upper respiratory tract infection
Chest pain
Decreased appetite
Dizziness
Dyspnoea exertional (breathlessness or shortness of breath)

What are the common drug interactions of Evoxac and Lansoprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Iron deficiency anaemia
Nasopharyngitis (inflammation of the nasopharynx)
Blood creatine phosphokinase increased
Gastroenteritis (inflammation of stomach and intestine)
Hyperlipidaemia (presence of excess lipids in the blood)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Osteonecrosis (death of bone)
Otitis externa (external ear infection)
Purpura (purplish discoloration of the skin)

30-39:

Platelet count decreased

40-49:

n/a

50-59:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Extranodal marginal zone b-cell lymphoma (malt type) (cancer originating from b cells in the marginal zone of the malt)
Flushing (the warm, red condition of human skin)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pneumonia
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Pyrexia (fever)
Rash

60+:

Dyspnoea (difficult or laboured respiration)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Application site pruritus (application site severe itching of the skin)
Application site rash
Aspartate aminotransferase increased
Blood sodium decreased
Cardiomyopathy (weakening of the heart muscle)
Chest pain
Chronic kidney disease
Confusional state

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 14 people, 36.84%
Hiv Infection: 6 people, 15.79%
Pain: 5 people, 13.16%
Multiple Myeloma (cancer of the plasma cells): 4 people, 10.53%
High Blood Pressure: 4 people, 10.53%
Pneumonia: 3 people, 7.89%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 3 people, 7.89%
High Blood Cholesterol: 3 people, 7.89%
Dry Mouth: 3 people, 7.89%
Gastric Disorder (disease of stomach): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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