Extavia and Naproxen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Extavia (interferon beta-1b) and Naproxen (naproxen). Common drug interactions include injection site erythema among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Extavia and Naproxen. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Extavia?

Extavia has active ingredients of interferon beta-1b. It is often used in multiple sclerosis. eHealthMe is studying from 4,888 Extavia users. Check the latest studies of Extavia.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

On Jul, 11, 2026

38 people who take Extavia and Naproxen together, and have interactions are studied.

What are the common drug interactions of Extavia and Naproxen, by gender? *:

female:

Injection site erythema (redness at injection site)
Injection site pain
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Migraine (headache)
Injection site haematoma (localized swelling filled with blood at injection site)
Headache (pain in head)
Fatigue (feeling of tiredness)
Memory impairment
Muscular weakness (muscle weakness)
Stress

male:

Fatigue (feeling of tiredness)
Headache (pain in head)
Gait disturbance
Muscular weakness (muscle weakness)
Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Urinary retention (the inability to completely or partially empty the bladder)
Vision blurred
Hepatic enzyme increased
Neuropathy peripheral (surface nerve damage)

What are the common drug interactions of Extavia and Naproxen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal discomfort
Chills (felling of cold)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Nervousness
Throat tightness

20-29:

Injection site haematoma (localized swelling filled with blood at injection site)
Optic neuritis (optic nerve inflammation)
Vitamin b12 deficiency
Vitamin d deficiency
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Device related infection
Intervertebral disc degeneration (spinal disc degeneration)
Platelet disorder
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

30-39:

Fatigue (feeling of tiredness)
Headache (pain in head)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Vision blurred
Muscular weakness (muscle weakness)
Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Migraine (headache)
Anxiety
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)

40-49:

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Blood pressure increased
Diplopia (double vision)
Dizziness
Injection site discolouration
Injection site pain
Injection site swelling
Lhermitte's sign (an electrical sensation that runs down the back and into the limbs)
Memory impairment
Stress

50-59:

Injection site erythema (redness at injection site)
Contusion (a type of hematoma of tissue in which capillaries)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Nasopharyngitis (inflammation of the nasopharynx)
Somnolence (a state of near-sleep, a strong desire for sleep)
Dizziness
Injection site bruising
Memory impairment
Asthenia (weakness)

60+:

n/a

* Approximation only. Some reports may have incomplete information.

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