Eylea and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eylea (aflibercept) and Acetaminophen (acetaminophen). Common drug interactions include infusion site haemorrhage among females and blindness among males.

The phase IV clinical study analyzes what interactions people have when they take Eylea and Acetaminophen. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 13, 2026

27 people who take Eylea and Acetaminophen together, and have interactions are studied.

Eylea and Acetaminophen drug interactions.

What are the common drug interactions of Eylea and Acetaminophen, by gender? *:

female:

Infusion site haemorrhage (bleeding from infusion site)
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
Nasal cyst (air or fluid filled sac of nose)
Sinusitis (inflammation of sinus)
Ankle fracture
Back pain
Diarrhoea
Fatigue (feeling of tiredness)
Muscle spasms (muscle contraction)
Sinus disorder (disease of sinus)

male:

Blindness
Fall
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Visual impairment
Death
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)

What are the common drug interactions of Eylea and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Death
Ankle fracture
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Herpes zoster
Intestinal obstruction
Joint dislocation (a joint position is changed from normal position)
Joint swelling
Muscular weakness (muscle weakness)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 12 people, 44.44%
Primary Immunodeficiency Syndrome: 5 people, 18.52%
Age-Related Macular Degeneration: 3 people, 11.11%
Neuropathy Peripheral (surface nerve damage): 2 people, 7.41%
Neuralgia (pain in one or more nerves): 2 people, 7.41%
Nausea (feeling of having an urge to vomit): 2 people, 7.41%
Constipation: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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