Ezetimibe and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ezetimibe (ezetimibe) and Prograf (tacrolimus). Common drug interactions include infusion site extravasation among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Ezetimibe and Prograf. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Ezetimibe?

Ezetimibe has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 30,849 Ezetimibe users. Check the latest studies of Ezetimibe.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.



On Jul, 11, 2026

45 people who take Ezetimibe and Prograf together, and have interactions are studied.

Ezetimibe and Prograf drug interactions.

What are the common drug interactions of Ezetimibe and Prograf, by gender? *:

female:

  1. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  2. Lip swelling
  3. Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue)
  4. Lymphadenopathy (disease or enlargement of lymph nodes)
  5. Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Oral disorder (mouth disease)
  8. Oropharyngeal pain
  9. Phaeochromocytoma (vascular tumour of the adrenal gland)
  10. Platelet count decreased

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Vomiting
  3. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  4. Loss of consciousness
  5. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  6. Pneumonia
  7. Renal failure acute (rapid kidney dysfunction)
  8. Renal failure chronic (long lasting kidney dysfunction)
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)

What are the common drug interactions of Ezetimibe and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Bacteriuria (presence of bacteria in urine)
  2. Blood glucose increased
  3. Glucose urine present
  4. Hypochloraemia (electrolyte disturbance in which there is an abnormally low level of the chloride ion in the blood)
  5. Lymphadenopathy (disease or enlargement of lymph nodes)
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Platelet count increased

30-39:

  1. Disease progression
  2. Drug ineffective
  3. Herpes zoster
  4. Infection
  5. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  6. Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
  7. Oropharyngeal pain
  8. Poor venous access
  9. White blood cell count decreased
  10. Complications of transplanted kidney

40-49:

  1. Dehydration (dryness resulting from the removal of water)
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Diabetic hyperosmolar coma (diabetes coma due to extremely high blood sugar (glucose) levels; extreme lack of water (dehydration))
  4. Fatigue (feeling of tiredness)
  5. Hyperkalaemia (damage to or disease of the kidney)
  6. Hyperosmolar state (life-threatening emergency manifested by marked elevation of blood glucose)
  7. Nausea (feeling of having an urge to vomit)
  8. Overdose
  9. Renal failure (kidney dysfunction)
  10. Visual impairment

50-59:

  1. Arthralgia (joint pain)
  2. Cataract (clouding of the lens inside the eye)
  3. Oral disorder (mouth disease)
  4. Pain in extremity
  5. Phaeochromocytoma (vascular tumour of the adrenal gland)
  6. Post procedural complication
  7. Staphylococcal infection (an infection with staphylococcus bacteria)

60+:

  1. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  2. Pneumonia
  3. Loss of consciousness
  4. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  5. Nausea (feeling of having an urge to vomit)
  6. Renal failure acute (rapid kidney dysfunction)
  7. Renal failure chronic (long lasting kidney dysfunction)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  10. Subdural haematoma (blood collects between the skull and the surface of the brain)

What are the existing conditions these people have? *

  1. High Blood Pressure: 16 people, 35.56%
  2. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Ezetimibe and Prograf?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ezetimibe and Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ezetimibe:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ezetimibe and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prograf and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ezetimibe and tacrolimus (the active ingredients of Ezetimibe and Prograf, respectively), and Ezetimibe and Prograf (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: