Famciclovir and Zosyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Famciclovir (famciclovir) and Zosyn (piperacillin sodium; tazobactam sodium). Common drug interactions include blood urea increased among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Famciclovir and Zosyn. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Famciclovir?

Famciclovir has active ingredients of famciclovir. It is often used in herpes zoster. eHealthMe is studying from 3,389 Famciclovir users. Check the latest studies of Famciclovir.

What is Zosyn?

Zosyn has active ingredients of piperacillin sodium; tazobactam sodium. It is often used in pneumonia. eHealthMe is studying from 10,236 Zosyn users. Check the latest studies of Zosyn.



On Jul, 16, 2026

12 people who take Famciclovir and Zosyn together, and have interactions are studied.

Famciclovir and Zosyn drug interactions.

What are the common drug interactions of Famciclovir and Zosyn, by gender? *:

female:

  1. Blood urea increased
  2. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  3. Encephalopathy (functioning of the brain is affected by some agent or condition)
  4. Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
  5. Vomiting
  6. Abasia (inability to walk)
  7. Abdominal pain upper
  8. Adenomatous polyposis coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine)
  9. Anaemia (lack of blood)
  10. Antiphospholipid antibodies positive

male:

  1. Anaemia (lack of blood)
  2. Colitis (inflammation of colon)
  3. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  4. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  5. Confusional state
  6. Deafness neurosensory
  7. Dementia (madness)
  8. Dyspepsia (indigestion)
  9. Dyspnoea (difficult or laboured respiration)
  10. Fall

What are the common drug interactions of Famciclovir and Zosyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Bk virus infection
  2. Blood albumin decreased
  3. Blood calcium decreased
  4. Blood chloride decreased
  5. Blood creatinine increased
  6. Blood glucose increased
  7. Blood osmolarity increased
  8. Blood phosphorus increased
  9. Blood potassium decreased
  10. Blood sodium decreased

20-29:

  1. Abdominal pain
  2. Alanine aminotransferase increased
  3. Aspartate aminotransferase increased
  4. Diarrhoea

30-39:

n/a

40-49:

  1. Anaemia (lack of blood)
  2. Drug eruption (adverse drug reaction of the skin)
  3. Drug hypersensitivity
  4. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  5. Low density lipoprotein increased (cholesterol increased in blood)
  6. Nephropathy toxic (damage to kidney due to toxins)
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Renal impairment (severely reduced kidney function)
  9. Upper respiratory tract inflammation
  10. White blood cell count decreased

50-59:

  1. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  2. Gingival pain (gum pain)
  3. Headache (pain in head)
  4. Nephropathy toxic (damage to kidney due to toxins)
  5. Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum)
  6. Transplant rejection (a transplant material is not worked)
  7. Abscess (pus)
  8. Cellulitis (infection under the skin)
  9. Drug hypersensitivity
  10. Fatigue (feeling of tiredness)

60+:

  1. Colitis (inflammation of colon)
  2. Anaemia (lack of blood)
  3. Bone loss
  4. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  5. Cardiomegaly (increased size of heart than normal)
  6. Cerebral atrophy (decrement in size of brain)
  7. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  8. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  9. Confusional state
  10. Deafness neurosensory

What are the existing conditions these people have? *

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 25.00%
  2. Metastases To Bone (cancer spreads to bone): 3 people, 25.00%
  3. Serum Ferritin Increased: 2 people, 16.67%
  4. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 16.67%
  5. Anaemia (lack of blood): 2 people, 16.67%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
  7. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 16.67%
  8. High Blood Pressure: 2 people, 16.67%
  9. Pneumonia: 1 person, 8.33%
  10. Immunodeficiency Common Variable: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Famciclovir and Zosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Famciclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Famciclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zosyn and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on famciclovir and piperacillin sodium; tazobactam sodium (the active ingredients of Famciclovir and Zosyn, respectively), and Famciclovir and Zosyn (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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