Fentora and Clonazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Fentora (fentanyl citrate) and Clonazepam (clonazepam). Common drug interactions include paraesthesia among females and drug dependence among males.
The phase IV clinical study analyzes what interactions people have when they take Fentora and Clonazepam. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.
What is Fentora?
Fentora has active ingredients of fentanyl citrate. eHealthMe is studying from 26,490 Fentora users. Check the latest studies of Fentora.
What is Clonazepam?
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.
40 people who take Fentora and Clonazepam together, and have interactions are studied.

What are the common drug interactions of Fentora and Clonazepam, by gender? *:
female:
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Paralysis
- Ph body fluid
- Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
- Polyarthritis (arthritis which involves 5 or more joints simultaneously)
- Post laminectomy syndrome
- Pulmonary oedema (fluid accumulation in the lungs)
- Pupil fixed
- Drug ineffective
- Loss of consciousness
male:
- Drug dependence
- Abdominal pain upper
- Emotional distress
- Fatigue (feeling of tiredness)
- International normalised ratio increased
- Muscle spasms (muscle contraction)
- Pain
- Pain in extremity
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pneumonia
What are the common drug interactions of Fentora and Clonazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Constipation
- Nasopharyngitis (inflammation of the nasopharynx)
- Upper-airway cough syndrome
30-39:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Juvenile myoclonic epilepsy (childhood epilepsy occurring early in morning affecting 12 to 18 years)
- Loss of consciousness
- Heart rate increased
- Hospitalisation
- Cardiac arrest
- Hypopnoea (decrease in the breathing rate)
- Stomatitis (inflammation of mucous membrane of mouth)
- Upper respiratory tract infection
- Blood pressure increased
40-49:
- Abdominal pain upper
- Abnormal dreams
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Delirium tremens (a psychotic condition typical of withdrawal in chronic alcoholics)
- Diarrhoea
- Drug dependence
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
50-59:
- Abdominal distension
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Atrioventricular block first degree (heart block first degree)
- Atrophy (wasting away of a part of the body)
- Back pain
- Blood pressure increased
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Chills (felling of cold)
60+:
- Drug ineffective
- Hyperhidrosis (abnormally increased sweating)
- International normalised ratio increased
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pneumonia
- Renal failure (kidney dysfunction)
- Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 45.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 17 people, 42.50%
- Pain: 5 people, 12.50%
- Cystitis Interstitial (unknown cause characterized by bladder pain): 4 people, 10.00%
- Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 3 people, 7.50%
- Breakthrough Pain: 3 people, 7.50%
- Migraine (headache): 2 people, 5.00%
- Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 5.00%
- High Blood Pressure: 2 people, 5.00%
- Depression: 2 people, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Fentora and Clonazepam?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Fentora (26,490 reports)
- Clonazepam (146,270 reports)
Browse all drug interactions of Fentora and Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Fentora:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fentora and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on fentanyl citrate and clonazepam (the active ingredients of Fentora and Clonazepam, respectively), and Fentora and Clonazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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