Fioricet and Remicade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fioricet (acetaminophen; butalbital; caffeine) and Remicade (infliximab). Common drug interactions include feeling hot among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Fioricet and Remicade. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Fioricet?

Fioricet has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 12,423 Fioricet users. Check the latest studies of Fioricet.

What is Remicade?

Remicade has active ingredients of infliximab. It is often used in crohn's disease. eHealthMe is studying from 224,011 Remicade users. Check the latest studies of Remicade.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

89 people who take Fioricet and Remicade together, and have interactions are studied.

Fioricet and Remicade drug interactions.

What are the common drug interactions of Fioricet and Remicade, by gender? *:

female:

Feeling hot
Gait disturbance
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Histoplasmosis (infection caused by breathing in spores of a fungus)
Hospitalisation
Limb discomfort (discomfort in leg)
Local swelling (swelling at the site of some application of substance or injury)
Infusion related reaction
Drug ineffective
Dyspnoea (difficult or laboured respiration)

male:

Pneumonia
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Infection
Lower respiratory tract infection bacterial
Meningitis meningococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
Protein s increased
Pulmonary mycosis (lung infection caused by yeast-like fungi)
Renal failure (kidney dysfunction)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Skin infection

What are the common drug interactions of Fioricet and Remicade, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Bacterial infection
Device related infection
Gastrointestinal viral infection (virus infection of gastrointestinal tract)
Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)

20-29:

Infusion related reaction
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Throat tightness
Agitation (state of anxiety or nervous excitement)
Arthralgia (joint pain)
Back pain
Blood pressure decreased
Hypersensitivity
Urticaria (rash of round, red welts on the skin that itch intensely)
Visual impairment

30-39:

Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
Drug ineffective
Hypersensitivity
Infusion related reaction
Joint swelling
Pain
Pain in extremity
Hospitalisation
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Abdominal pain

40-49:

Dysphagia (a condition in which swallowing is difficult or painful)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Throat irritation
Throat tightness
Tremor (trembling or shaking movements in one or more parts of your body)
Anaphylactic reaction (serious allergic reaction)
Arthralgia (joint pain)
Chest pain
Collapse of lung (functional breakdown of lung)

50-59:

Pain in extremity
Drug ineffective
Gout (uric acid crystals building up in the body)
Injection site bruising
Injection site haemorrhage (bleeding from injection site)
Pain
Swelling
Peripheral swelling
Local swelling (swelling at the site of some application of substance or injury)
Insomnia (sleeplessness)

60+:

Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Back pain
Cellulitis (infection under the skin)
Chest pain
Drug ineffective
Fall

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 21 people, 23.60%
Pain: 16 people, 17.98%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 15.73%
Inflammatory Bowel Disease: 11 people, 12.36%
Headache (pain in head): 9 people, 10.11%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 6 people, 6.74%
Dry Mouth: 5 people, 5.62%

* Approximation only. Some reports may have incomplete information.

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