Fioricet and Zelnorm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fioricet (acetaminophen; butalbital; caffeine) and Zelnorm (tegaserod maleate). Common drug interactions include seasonal allergy among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Fioricet and Zelnorm. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Fioricet?

Fioricet has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 12,423 Fioricet users. Check the latest studies of Fioricet.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.

On Jul, 26, 2026

21 people who take Fioricet and Zelnorm together, and have interactions are studied.

What are the common drug interactions of Fioricet and Zelnorm, by gender? *:

female:

Seasonal allergy (allergic condition due to certain season)
Tremor (trembling or shaking movements in one or more parts of your body)
Urinary tract infection
Anxiety
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Back pain
Depressed mood
Diarrhoea
Drug ineffective

male:

Dizziness
Heart rate increased
Hypotension (abnormally low blood pressure)
Fatigue (feeling of tiredness)
Heart rate irregular

What are the common drug interactions of Fioricet and Zelnorm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dyspnoea exertional (breathlessness or shortness of breath)
Pulmonary embolism (blockage of the main artery of the lung)
Seasonal allergy (allergic condition due to certain season)
Urinary tract infection
Hypercoagulation (increased tendency for clotting of the blood)
Hypervolaemia (abnormally increased volume of blood)
Ovarian cyst (fluid filled sac of the ovary)
Pain
Swelling
Abdominal pain

40-49:

Abdominal distension
Abdominal pain
Constipation
Diarrhoea
Dizziness
Pain
Tremor (trembling or shaking movements in one or more parts of your body)
Alanine aminotransferase increased
Anaemia (lack of blood)
Anxiety

50-59:

Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Aspartate aminotransferase increased
Atelectasis (partial or complete collapse of the lung)
Biliary dilatation
Blood bicarbonate decreased
Blood glucose increased
Deafness
Depressed mood
Drug ineffective

60+:

Dizziness
Heart rate increased
Hypotension (abnormally low blood pressure)
Abdominal pain upper
Diarrhoea
Fatigue (feeling of tiredness)
Gastric irritation (stomach irritation)
Heart rate irregular

What are the existing conditions these people have? *

Irritable Bowel Syndrome: 10 people, 47.62%
Pain: 5 people, 23.81%
Constipation: 5 people, 23.81%
Hypersensitivity: 3 people, 14.29%
Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 9.52%
Headache (pain in head): 2 people, 9.52%
Disturbance In Attention: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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