Flavin and Morphine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flavin (riboflavin (vitamin b2)) and Morphine (morphine sulfate). Common drug interactions include cholelithiasis among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Flavin and Morphine. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Flavin?

Flavin has active ingredients of riboflavin (vitamin b2). eHealthMe is studying from 2,870 Flavin users. Check the latest studies of Flavin.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

On Jul, 17, 2026

64 people who take Flavin and Morphine together, and have interactions are studied.

What are the common drug interactions of Flavin and Morphine, by gender? *:

female:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Fatigue (feeling of tiredness)
Muscle atrophy (a decrease in the mass of the muscle)
Therapeutic response decreased (less preventive response)
Abdominal discomfort
Abdominal distension
Arthropathy
Blood glucose decreased
Cardiac arrest
Cough

male:

Diarrhoea
Chronic kidney disease
Gait disturbance
Hepatitis acute
Intervertebral disc protrusion (spinal disc protrusion)
Liver injury
Malignant neoplasm progression (cancer tumour came back)
Mobility decreased (ability to move is reduced)
Nerve compression
Osteoporosis (bones weak and more likely to break)

What are the common drug interactions of Flavin and Morphine, by age (0-1 to 60+)? *:

0-1:

Abdominal distension
Acidosis (build-up of carbon dioxide in the blood)
Activities of daily living impaired
Anuria (failure of the kidneys to produce urine)
Aortic valve incompetence
Apnoea (suspension of external breathing)
Arrhythmia (irregular heartbeat)
Atelectasis (partial or complete collapse of the lung)
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

2-9:

Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Febrile neutropenia (fever with reduced white blood cells)
Malignant neoplasm progression (cancer tumour came back)
Refractory cancer (cancer that has not responded to treatment)
Upper respiratory tract infection

10-19:

n/a

20-29:

n/a

30-39:

Complication of delivery
Dysphagia (a condition in which swallowing is difficult or painful)
Fibromyalgia (a long-term condition which causes pain all over the body)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Maternal exposure before pregnancy (use of substance before pregnancy)
Overdose
Premature delivery
Vomiting

40-49:

Varicose vein ruptured
Abdominal pain
Cellulitis (infection under the skin)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diarrhoea
Dizziness
Fatigue (feeling of tiredness)
Fistula (an abnormal connection or passageway between two)
Weight decreased
Optic neuropathy (optic nerve damage)

50-59:

Tremor (trembling or shaking movements in one or more parts of your body)
Urticaria (rash of round, red welts on the skin that itch intensely)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Anxiety
Chronic kidney disease
Decreased activity
Depression
Emotional distress
Gait disturbance

60+:

Headache (pain in head)
Colitis (inflammation of colon)
Erythema (redness of the skin)
Female genital tract fistula (passage in genital tract of female)
Frequent bowel movements
Haematochezia (passage of stools containing blood)
Infusion related reaction
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 10 people, 15.62%
Diarrhea: 9 people, 14.06%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 12.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 12.50%
Insomnia (sleeplessness): 8 people, 12.50%
High Blood Pressure: 8 people, 12.50%
High Blood Cholesterol: 7 people, 10.94%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 10.94%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 9.38%
Constipation: 6 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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