Flector and Glucophage drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flector (diclofenac epolamine) and Glucophage (metformin hydrochloride). Common drug interactions include renal artery stenosis among females and haemorrhagic anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Flector and Glucophage. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Flector?

Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 5,112 Flector users. Check the latest studies of Flector.

What is Glucophage?

Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.

On Jul, 17, 2026

38 people who take Flector and Glucophage together, and have interactions are studied.

Flector and Glucophage drug interactions.

What are the common drug interactions of Flector and Glucophage, by gender? *:

female:

Renal artery stenosis (narrowing of renal artery)
Renal failure (kidney dysfunction)
Dehydration (dryness resulting from the removal of water)
Hyperkalaemia (damage to or disease of the kidney)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Diarrhoea
Hypotension (abnormally low blood pressure)
Arthropathy
Back injury
Balance disorder

male:

Haemorrhagic anaemia (anaemia due to excessive bleeding)
Melaena (the passage of black, tarry stools)
Mitral valve incompetence (inefficient heart valve)
Hypotonia (low muscle tone)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Vascular occlusion (sudden blockage of a blood vessel, usually with a clot)
Renal failure acute (rapid kidney dysfunction)
Anaemia (lack of blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)

What are the common drug interactions of Flector and Glucophage, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abasia (inability to walk)
Arthralgia (joint pain)
Blood creatine phosphokinase increased
Blood glucose increased
Bone pain
Myalgia (muscle pain)
Pancreatitis acute (sudden inflammation of pancreas)

50-59:

Abscess (pus)
Carotid intima-media thickness increased (increased thickness of carotid artery muscle)
Cellulitis (infection under the skin)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypotension (abnormally low blood pressure)
Mitral valve incompetence (inefficient heart valve)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)
Presyncope

60+:

Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Cardiovascular disorder (heart diseases)
Carotid artery occlusion (artery blockage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Device occlusion
Diarrhoea
Dizziness
Ear infection viral

What are the existing conditions these people have? *

Type 2 Diabetes: 9 people, 23.68%
High Blood Pressure: 8 people, 21.05%
Infection: 7 people, 18.42%
Bipolar Disorder (mood disorder): 7 people, 18.42%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 7 people, 18.42%
Depression: 6 people, 15.79%
Glaucoma (increased fluid pressure in the eye with vision loss): 6 people, 15.79%
High Blood Cholesterol: 5 people, 13.16%
Blood Pressure Abnormal: 5 people, 13.16%
Cardiac Disorder: 5 people, 13.16%

* Approximation only. Some reports may have incomplete information.

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