Flonase and Anzemet drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Flonase (fluticasone propionate) and Anzemet (dolasetron mesylate). Common drug interactions include bone pain among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Flonase and Anzemet. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.
What is Flonase?
Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.
What is Anzemet?
Anzemet has active ingredients of dolasetron mesylate. eHealthMe is studying from 2,603 Anzemet users. Check the latest studies of Anzemet.
72 people who take Flonase and Anzemet together, and have interactions are studied.

What are the common drug interactions of Flonase and Anzemet, by gender? *:
female:
- Bone pain
- Diarrhoea
- Pain in jaw
- Pleural effusion (water on the lungs)
- Tooth abscess (pus formation in tooth)
- Dental caries
- Mouth ulceration (mouth ulcers)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
- Tricuspid valve incompetence (inefficient heart valve)
male:
- Diarrhoea
- Dizziness
- Balance disorder
- Biliary dilatation
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Bone marrow oedema (inflammation that causes much than the needed fluid in a bone)
- Bone pain
- Carcinoid syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction)
- Carcinoid tumour of the small bowel
- Cellulitis (infection under the skin)
What are the common drug interactions of Flonase and Anzemet, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abdominal discomfort
- Agitation (state of anxiety or nervous excitement)
- Anaphylactic reaction (serious allergic reaction)
- Cardiac arrest
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Dyspnoea (difficult or laboured respiration)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Restlessness (not able to rest)
40-49:
- Alopecia (absence of hair from areas of the body)
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Artificial menopause
- Atelectasis (partial or complete collapse of the lung)
- Bone pain
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Depression
50-59:
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Appendicitis (inflammation of the appendix)
- Aptyalism (deficiency or absence of saliva)
- Asthma
- Bone disorder
- Bone erosion
- Bone fragmentation
- Bone pain
- Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
- Cellulitis (infection under the skin)
60+:
- Diarrhoea
- Abdominal pain
- Haemoglobin decreased
- Headache (pain in head)
- Hypertension (high blood pressure)
- Injury
- Pain
- Anaemia (lack of blood)
- Anaemia of malignant disease
- Anaemia vitamin b12 deficiency
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 23 people, 31.94%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 19 people, 26.39%
- Sleep Disorder: 18 people, 25.00%
- Depression: 18 people, 25.00%
- Muscle Spasms (muscle contraction): 17 people, 23.61%
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 17 people, 23.61%
- Osteoporosis (bones weak and more likely to break): 9 people, 12.50%
- Metastases To Bone (cancer spreads to bone): 9 people, 12.50%
- Thrombocytopenia (decrease of platelets in blood): 8 people, 11.11%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 8 people, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Flonase and Anzemet?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Flonase and Anzemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Anzemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flonase and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Anzemet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on fluticasone propionate and dolasetron mesylate (the active ingredients of Flonase and Anzemet, respectively), and Flonase and Anzemet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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