Flonase and Combivir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flonase (fluticasone propionate) and Combivir (lamivudine; zidovudine). Common drug interactions include pneumonia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Flonase and Combivir. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.



On Jul, 11, 2026

55 people who take Flonase and Combivir together, and have interactions are studied.

Flonase and Combivir drug interactions.

What are the common drug interactions of Flonase and Combivir, by gender? *:

female:

  1. Pneumonia
  2. Pyrexia (fever)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Sleep disorder
  5. Tooth loss
  6. Death
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Anxiety
  9. Emotional distress
  10. Pain

male:

  1. Pain
  2. Anxiety
  3. Renal failure (kidney dysfunction)
  4. Renal impairment (severely reduced kidney function)
  5. Bone density decreased
  6. Anger
  7. Blood creatinine increased
  8. Bone marrow disorder
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Decreased activity

What are the common drug interactions of Flonase and Combivir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Hepatitis (inflammation of the liver)
  2. Pancreatitis (inflammation of pancreas)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Blood phosphorus decreased
  6. Decreased activity
  7. Depression
  8. Dyspepsia (indigestion)
  9. Dyspnoea (difficult or laboured respiration)
  10. Emotional distress

30-39:

  1. Pyrexia (fever)
  2. Abdominal pain
  3. Acute respiratory failure
  4. Cardiac failure congestive
  5. Congestive cardiomyopathy (weakening of heart muscle)
  6. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  7. Dyspnoea (difficult or laboured respiration)
  8. General physical health deterioration (weak health status)
  9. H1n1 influenza (flu (influenza), which is caused by virus influenza a (h1n1))
  10. Headache (pain in head)

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Emotional distress
  5. Pain
  6. Depression
  7. Osteoporosis (bones weak and more likely to break)
  8. Asthenia (weakness)
  9. Bone density decreased
  10. Cervical spinal stenosis (narrowing of the spinal canal in the neck)

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Chronic kidney disease
  6. Osteopenia (a condition where bone mineral density is lower than normal)
  7. Death
  8. Depression
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  10. Bone density decreased

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Pneumonia
  4. Renal failure (kidney dysfunction)
  5. Sleep disorder
  6. Chronic kidney disease
  7. Diarrhoea
  8. Emotional distress
  9. Hypoxia (low oxygen in tissues)
  10. Maternal exposure during pregnancy (use of substance during pregnancy)

What are the existing conditions these people have? *

  1. Hiv Infection: 37 people, 67.27%
  2. High Blood Pressure: 6 people, 10.91%
  3. Pain: 5 people, 9.09%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.09%
  5. Stress And Anxiety: 4 people, 7.27%
  6. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 5.45%
  7. Hypersensitivity: 3 people, 5.45%
  8. Bacterial Infection: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Do you take Flonase and Combivir?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flonase and Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flonase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flonase and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fluticasone propionate and lamivudine; zidovudine (the active ingredients of Flonase and Combivir, respectively), and Flonase and Combivir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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