Flonase and Flector drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flonase (fluticasone propionate) and Flector (diclofenac epolamine). Common drug interactions include abdominal pain upper among females and subdural haematoma among males.

The phase IV clinical study analyzes what interactions people have when they take Flonase and Flector. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

What is Flector?

Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 5,112 Flector users. Check the latest studies of Flector.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

93 people who take Flonase and Flector together, and have interactions are studied.

What are the common drug interactions of Flonase and Flector, by gender? *:

female:

Abdominal pain upper
Abdominal wall haemorrhage (bleeding from injured abdominal organs)
Anaemia (lack of blood)
Overdose
Drug ineffective
Diarrhoea
Anxiety
Renal failure (kidney dysfunction)
Pancreatitis (inflammation of pancreas)
Polymyalgia rheumatica (pain in many muscles)

male:

Subdural haematoma (blood collects between the skull and the surface of the brain)
Arthralgia (joint pain)
Disability
Drug effect decreased
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysgeusia (disorder of the sense of taste)
Headache (pain in head)
Palpitations (feelings or sensations that your heart is pounding or racing)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Pruritus (severe itching of the skin)

What are the common drug interactions of Flonase and Flector, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal wall haemorrhage (bleeding from injured abdominal organs)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Dysgeusia (disorder of the sense of taste)
Pruritus (severe itching of the skin)
Arthralgia (joint pain)
Drug ineffective
Erythema (redness of the skin)
Hypersensitivity
Rash
Throat irritation
Abdominal pain
Chills (felling of cold)

50-59:

Drug hypersensitivity
Ear infection
Fibrocystic breast disease (a condition causing breast pain, cysts, and noncancerous breast lumps, affects many women)
Hepatic steatosis (fatty liver disease)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypertension (high blood pressure)
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Kidney infection

60+:

Overdose
Anxiety
Cataract (clouding of the lens inside the eye)
Drug ineffective
Fluid retention (an abnormal accumulation of fluid in the blood)
Gait disturbance
Glycosylated haemoglobin increased
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 21 people, 22.58%
High Blood Pressure: 18 people, 19.35%
Hypersensitivity: 15 people, 16.13%
Sleep Disorder: 13 people, 13.98%
Fibromyalgia (a long-term condition which causes pain all over the body): 12 people, 12.90%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 11.83%
Asthma: 10 people, 10.75%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 10 people, 10.75%
Nausea (feeling of having an urge to vomit): 10 people, 10.75%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 9.68%

* Approximation only. Some reports may have incomplete information.

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