Flonase and Kelnor drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Flonase (fluticasone propionate) and Kelnor (ethinyl estradiol; ethynodiol diacetate). Common drug interactions include injection site bruising among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Flonase and Kelnor. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Flonase?
Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.
What is Kelnor?
Kelnor has active ingredients of ethinyl estradiol; ethynodiol diacetate. It is often used in birth control. eHealthMe is studying from 211 Kelnor users. Check the latest studies of Kelnor.
11 people who take Flonase and Kelnor together, and have interactions are studied.

What are the common drug interactions of Flonase and Kelnor, by gender? *:
female:
- Injection site bruising
- Nasal disorder (diseases of nose)
- Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Weight increased
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Asthenia (weakness)
- Urinary tract infection
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
male:
- Death
- Drug administration error
What are the common drug interactions of Flonase and Kelnor, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Nightmare (unpleasant dream)
- Nasal disorder (diseases of nose)
30-39:
n/a
40-49:
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Urinary tract infection
50-59:
- Death
- Drug administration error
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 54.55%
- Hypersensitivity: 6 people, 54.55%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 27.27%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%
- Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups): 1 person, 9.09%
- Stress And Anxiety: 1 person, 9.09%
- Sleep Disorder: 1 person, 9.09%
- Premenstrual Dysphoric Disorder: 1 person, 9.09%
- Panic Disorder: 1 person, 9.09%
- Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Flonase and Kelnor?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Flonase and Kelnor:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Kelnor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flonase and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Kelnor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on fluticasone propionate and ethinyl estradiol; ethynodiol diacetate (the active ingredients of Flonase and Kelnor, respectively), and Flonase and Kelnor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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