Flonase and Loprox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Flonase (fluticasone propionate) and Loprox (ciclopirox). Common drug interactions include left ventricular failure among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Flonase and Loprox. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Flonase?
Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.
What is Loprox?
Loprox has active ingredients of ciclopirox. eHealthMe is studying from 618 Loprox users. Check the latest studies of Loprox.
36 people who take Flonase and Loprox together, and have interactions are studied.

What are the common drug interactions of Flonase and Loprox, by gender? *:
female:
- Left ventricular failure (left ventricle fails to contract forcefully)
- Lichen planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash)
- Loose stools
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Eustachian tube dysfunction (eustachian tube problems like clearing the ears when flying, suffering infection, and recurring ear infection)
- Otitis media acute (rapid inflammation of the middle ear)
- Pathological gambling
- Pharyngitis (inflammation of the pharynx, causing a sore throat)
- Psychiatric symptom
- Tracheitis (an inflammation of the trachea)
male:
- Death
- Ammonia increased
- Neuralgia (pain in one or more nerves)
- Pain
- Pelvic fracture
- Rehabilitation therapy
- Asthenia (weakness)
- Clavicle fracture
- Constipation
- Disturbance in attention
What are the common drug interactions of Flonase and Loprox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Urinary tract infection
- Vaginal infection
- Drug effect decreased
- Anaemia (lack of blood)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Disturbance in attention
- Gastrointestinal infection (infection of stomach and intestine)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Hypertension (high blood pressure)
50-59:
n/a
60+:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Eustachian tube dysfunction (eustachian tube problems like clearing the ears when flying, suffering infection, and recurring ear infection)
- Constipation
- Nausea (feeling of having an urge to vomit)
- Abdominal pain
- Acarodermatitis (skin inflammation caused by mites (acarids))
- Alopecia (absence of hair from areas of the body)
- Ammonia increased
- Anaemia (lack of blood)
- Anaphylactic reaction (serious allergic reaction)
What are the existing conditions these people have? *
- High Blood Pressure: 18 people, 50.00%
- Allergic Rhinitis: 12 people, 33.33%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 12 people, 33.33%
- Stress And Anxiety: 12 people, 33.33%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 12 people, 33.33%
- Ear Barotrauma (discomfort and possible damage in the ear due to pressure differences between the inside and outside of the eardrum): 12 people, 33.33%
- Restless Leg Syndrome (a powerful urge to move your legs): 12 people, 33.33%
- Panic Disorder: 12 people, 33.33%
- Sinusitis (inflammation of sinus): 11 people, 30.56%
- Pain: 10 people, 27.78%
* Approximation only. Some reports may have incomplete information.
Do you take Flonase and Loprox?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Flonase and Loprox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Loprox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flonase and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Loprox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on fluticasone propionate and ciclopirox (the active ingredients of Flonase and Loprox, respectively), and Flonase and Loprox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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