Flonase and Ocaliva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flonase (fluticasone propionate) and Ocaliva (obeticholic acid). Common drug interactions include pruritus among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Flonase and Ocaliva. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

What is Ocaliva?

Ocaliva has active ingredients of obeticholic acid. eHealthMe is studying from 6,919 Ocaliva users. Check the latest studies of Ocaliva.

On Aug, 08, 2026

55 people who take Flonase and Ocaliva together, and have interactions are studied.

What are the common drug interactions of Flonase and Ocaliva, by gender? *:

female:

Pruritus (severe itching of the skin)
Fatigue (feeling of tiredness)
Arthralgia (joint pain)
Nausea (feeling of having an urge to vomit)
Blood alkaline phosphatase increased
Constipation
Hyperhidrosis (abnormally increased sweating)
Pain
Pneumonia
Hypotension (abnormally low blood pressure)

male:

Acute respiratory failure
Anaemia (lack of blood)
Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)
Renal failure (kidney dysfunction)
Septic shock (shock due to blood infection)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Cardiac failure
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Haemorrhage (bleeding)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)

What are the common drug interactions of Flonase and Ocaliva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)

50-59:

Glomerular filtration rate decreased
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hypersensitivity
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Protein total decreased
Pruritus (severe itching of the skin)
Dyspepsia (indigestion)
Fluid retention (an abnormal accumulation of fluid in the blood)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hepatic steatosis (fatty liver disease)

60+:

Pruritus (severe itching of the skin)
Fatigue (feeling of tiredness)
Pyrexia (fever)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Gait disturbance
Abdominal pain upper
Bedridden
Colonoscopy
Decreased activity
Dizziness

What are the existing conditions these people have? *

Biliary Cirrhosis Primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver): 7 people, 12.73%

* Approximation only. Some reports may have incomplete information.

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