Tarka and Flonase drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tarka (trandolapril; verapamil hydrochloride) and Flonase (fluticasone propionate). Common drug interactions include headache among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Tarka and Flonase. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Tarka?
Tarka has active ingredients of trandolapril; verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,409 Tarka users. Check the latest studies of Tarka.
What is Flonase?
Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,439 Flonase users. Check the latest studies of Flonase.
12 people who take Tarka and Flonase together, and have interactions are studied.

What are the common drug interactions of Tarka and Flonase, by gender? *:
female:
- Headache (pain in head)
- Insomnia (sleeplessness)
- Loss of consciousness
- Oedema peripheral (superficial swelling)
- Pleural effusion (water on the lungs)
- Pyrexia (fever)
- Ruptured cerebral aneurysm (bleeding from brain)
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Urate nephropathy (disease or abnormality of the kidney)
male:
- Fall
- Nausea (feeling of having an urge to vomit)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Back pain
- Blood bilirubin increased
- Bone infarction (ischemic death of the cellular elements of the bone and marrow)
- Calculus ureteric (stone in ureter)
- Cellulitis (infection under the skin)
- Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
What are the common drug interactions of Tarka and Flonase, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abdominal pain upper
- Blood bilirubin increased
- Cholangitis (infection of the bile duct)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Escherichia sepsis (bacterial infection by escherichia coli)
- Nausea (feeling of having an urge to vomit)
- Pancreatic enzymes increased
- Pancreatitis (inflammation of pancreas)
- Pyrexia (fever)
- Vomiting
40-49:
n/a
50-59:
- Chronic kidney disease
- Gingival abscess (pus in gums)
- Pyrexia (fever)
- Renal failure (kidney dysfunction)
- Urate nephropathy (disease or abnormality of the kidney)
- Erythema (redness of the skin)
- Fall
- Gait disturbance
- Hypoaesthesia (reduced sense of touch or sensation)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
60+:
- Chest pain
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
- Dehydration (dryness resulting from the removal of water)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Fall
- Loss of consciousness
- Pleural effusion (water on the lungs)
- Ruptured cerebral aneurysm (bleeding from brain)
- Abdominal adhesions (inflammation of abdomen)
What are the existing conditions these people have? *
- Pain: 4 people, 33.33%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 25.00%
- Stress And Anxiety: 2 people, 16.67%
- High Blood Cholesterol: 2 people, 16.67%
- Back Pain: 2 people, 16.67%
- Depression: 2 people, 16.67%
- Diabetes: 2 people, 16.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
- Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 16.67%
- Indigestion: 2 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Tarka and Flonase?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tarka and Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tarka:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tarka and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flonase and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on trandolapril; verapamil hydrochloride and fluticasone propionate (the active ingredients of Tarka and Flonase, respectively), and Tarka and Flonase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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