Flovent and Alupent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flovent (fluticasone propionate) and Alupent (metaproterenol sulfate). Common drug interactions include blood potassium decreased among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Flovent and Alupent. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Flovent?

Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.

What is Alupent?

Alupent has active ingredients of metaproterenol sulfate. eHealthMe is studying from 604 Alupent users. Check the latest studies of Alupent.

On Jul, 20, 2026

65 people who take Flovent and Alupent together, and have interactions are studied.

What are the common drug interactions of Flovent and Alupent, by gender? *:

female:

Blood potassium decreased
Body temperature increased
Collapse (sudden functional breakdown)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haematocrit decreased
Haemoglobin decreased
Nausea (feeling of having an urge to vomit)
Protein total decreased
Regurgitation of food (expulsion of material from the mouth, pharynx, or oesophagus)
Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle)

male:

Hypertension (high blood pressure)
Churg strauss syndrome (infection of small arteries and vein)
Pain in limb
Pulmonary congestion (congestion in the lungs)
Abdominal distension
Anaphylactic reaction (serious allergic reaction)
Arthralgia (joint pain)
Back pain
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cardiac murmur (an heart sound in valve abnormality)

What are the common drug interactions of Flovent and Alupent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abnormal labour
Dry mouth
Urinary retention (the inability to completely or partially empty the bladder)

40-49:

Abdominal distension
Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Application site reaction
Bronchospasm paradoxical (a constriction of the airways after treatment with a sympathomimetic bronchodilator)
Chest pain
Chronic kidney disease
Comminuted fracture (bone has broken into several pieces)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Drug effect decreased
Dyspnoea (difficult or laboured respiration)

50-59:

International normalised ratio increased
Activated partial thromboplastin time prolonged
Acute myocardial infarction (acute heart attack)
Platelet count decreased
Blood pressure increased
Gastritis (inflammation of stomach)
Atelectasis (partial or complete collapse of the lung)
Pleuritic pain
Haematemesis (vomiting of blood)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)

60+:

Anxiety
Emotional distress
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Back pain
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
White blood cell count increased
Blood potassium decreased
Churg strauss syndrome (infection of small arteries and vein)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 4 people, 6.15%

* Approximation only. Some reports may have incomplete information.

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