Trulicity and Prinivil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trulicity (dulaglutide) and Prinivil (lisinopril). Common drug interactions include cough among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Trulicity and Prinivil. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.



On Jul, 20, 2026

35 people who take Trulicity and Prinivil together, and have interactions are studied.

Trulicity and Prinivil drug interactions.

What are the common drug interactions of Trulicity and Prinivil, by gender? *:

female:

  1. Cough
  2. Diarrhoea
  3. Dizziness
  4. Erythema (redness of the skin)
  5. Eye pain
  6. Glycosylated haemoglobin decreased
  7. Glycosylated haemoglobin increased
  8. Headache (pain in head)
  9. Hyperlipidaemia (presence of excess lipids in the blood)
  10. Intervertebral disc protrusion (spinal disc protrusion)

male:

  1. Diarrhoea
  2. Fatigue (feeling of tiredness)
  3. Chronic kidney disease
  4. Drug intolerance (drug sensitivity)
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Emotional distress
  7. Genital lesion (sores, warts, or blemishes that appear on the genitals)
  8. Groin abscess (pus in groin)
  9. Hyperlipidaemia (presence of excess lipids in the blood)
  10. Perineal pain

What are the common drug interactions of Trulicity and Prinivil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abscess limb (limb infection)
  2. Groin abscess (pus in groin)
  3. Anal abscess
  4. Anxiety
  5. Genital abscess (build up of pus in genital)
  6. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  7. Nerve injury
  8. Pain
  9. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  10. Perineal abscess

40-49:

  1. Abscess limb (limb infection)
  2. Anxiety
  3. Depression
  4. Fatigue (feeling of tiredness)
  5. Groin abscess (pus in groin)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  8. Nervousness
  9. Overdose
  10. Perineal abscess

50-59:

  1. Emotional distress
  2. Pain
  3. Genital lesion (sores, warts, or blemishes that appear on the genitals)
  4. Perineal pain
  5. Rectal abscess (pus in rectum)
  6. Scrotal swelling
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Testicular pain (pain in testes)
  9. Bacterial sepsis
  10. Blindness

60+:

  1. Diarrhoea
  2. Diabetic amyotrophy (painful asymmetrical proximal motor neuropathy affecting the lower limbs)
  3. Respiratory disorder (respiratory disease)
  4. Vertigo
  5. Diabetic foot
  6. Gangrene (body tissue dies)
  7. Asthenia (weakness)
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Fall
  10. Pain

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 16 people, 45.71%
  2. Diabetes: 7 people, 20.00%
  3. Pain: 6 people, 17.14%
  4. Weight Decreased: 6 people, 17.14%
  5. Blood Pressure Abnormal: 4 people, 11.43%
  6. Hypotension (abnormally low blood pressure): 4 people, 11.43%
  7. Bipolar Disorder (mood disorder): 3 people, 8.57%
  8. Idiopathic Pulmonary Fibrosis (chronic lung disease): 3 people, 8.57%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.57%
  10. Gout (uric acid crystals building up in the body): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trulicity and Prinivil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prinivil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trulicity and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prinivil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dulaglutide and lisinopril (the active ingredients of Trulicity and Prinivil, respectively), and Trulicity and Prinivil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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