Fluconazole and Misoprostol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluconazole (fluconazole) and Misoprostol (misoprostol). Common drug interactions include drug ineffective among females and drug resistance among males.

The phase IV clinical study analyzes what interactions people have when they take Fluconazole and Misoprostol. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

What is Misoprostol?

Misoprostol has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 8,222 Misoprostol users. Check the latest studies of Misoprostol.



On Jul, 25, 2026

91 people who take Fluconazole and Misoprostol together, and have interactions are studied.

Fluconazole and Misoprostol drug interactions.

What are the common drug interactions of Fluconazole and Misoprostol, by gender? *:

female:

  1. Drug ineffective
  2. Escherichia sepsis (bacterial infection by escherichia coli)
  3. Femoral neck fracture (neck of femur bone fracture)
  4. Gastric ulcer (stomach ulcer)
  5. Groin abscess (pus in groin)
  6. Hypokalaemia (low potassium)
  7. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  8. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  9. Myalgia (muscle pain)
  10. Oedema peripheral (superficial swelling)

male:

  1. Drug resistance (reduction in effectiveness of a drug)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Pain
  4. Quality of life decreased
  5. Rib fracture
  6. Spinal fracture (fracture in one of vertebrae)
  7. Upper limb fracture
  8. Overdose
  9. Acute circulatory failure (shock)
  10. Osteopenia (a condition where bone mineral density is lower than normal)

What are the common drug interactions of Fluconazole and Misoprostol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Pain
  2. Chronic kidney disease
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Crying
  6. Depression suicidal (suicide depressive disorder)
  7. Emotional distress
  8. Osteoporosis (bones weak and more likely to break)
  9. Quality of life decreased
  10. Renal failure (kidney dysfunction)

30-39:

  1. Drug resistance (reduction in effectiveness of a drug)
  2. Haemorrhage in pregnancy (bleeding in pregnancy)
  3. Iron deficiency
  4. Maternal exposure during pregnancy (use of substance during pregnancy)
  5. Vulvovaginal mycotic infection (vulvovaginal fungal infection)
  6. Cryptococcosis (potentially fatal fungal disease)
  7. Lung disorder (lung disease)
  8. Overdose
  9. Blood magnesium decreased
  10. Cardiac arrest

40-49:

  1. Perirectal abscess
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Tooth abscess (pus formation in tooth)
  4. Urinary tract infection
  5. Vulval abscess
  6. Abdominal distension
  7. Carbuncle (a carbuncle is an abscess larger than a boil)
  8. Complication of device insertion
  9. Cushing's syndrome (obesity, a rounded face, increased fat)
  10. Death

50-59:

  1. Chronic kidney disease
  2. Depression
  3. Diarrhoea
  4. Gastric ulcer (stomach ulcer)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Pyrexia (fever)
  7. Acute circulatory failure (shock)
  8. Acute myocardial infarction (acute heart attack)
  9. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  10. Cataract (clouding of the lens inside the eye)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Cellulitis (infection under the skin)
  4. Drug ineffective
  5. Hypotension (abnormally low blood pressure)
  6. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  7. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  8. Nephropathy (damage to or disease of a kidney)
  9. Oedema peripheral (superficial swelling)
  10. Oropharyngeal pain

What are the existing conditions these people have? *

  1. Pain: 21 people, 23.08%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 19 people, 20.88%
  3. Depression: 16 people, 17.58%
  4. High Blood Cholesterol: 14 people, 15.38%
  5. High Blood Pressure: 14 people, 15.38%
  6. Inflammation: 11 people, 12.09%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 10.99%
  8. Hypersensitivity: 9 people, 9.89%
  9. Muscle Spasms (muscle contraction): 9 people, 9.89%
  10. Infection: 9 people, 9.89%

* Approximation only. Some reports may have incomplete information.

Do you take Fluconazole and Misoprostol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fluconazole and Misoprostol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Misoprostol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fluconazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Misoprostol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluconazole and misoprostol (the active ingredients of Fluconazole and Misoprostol, respectively), and Fluconazole and Misoprostol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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