Fluoxetine hydrochloride and Flonase allergy relief drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluoxetine hydrochloride (fluoxetine hydrochloride) and Flonase allergy relief (fluticasone propionate). Common drug interactions include therapeutic response decreased among females and arteriosclerosis among males.

The phase IV clinical study analyzes what interactions people have when they take Fluoxetine hydrochloride and Flonase allergy relief. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Fluoxetine hydrochloride?

Fluoxetine hydrochloride has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 13,381 Fluoxetine hydrochloride users. Check the latest studies of Fluoxetine hydrochloride.

What is Flonase allergy relief?

Flonase allergy relief has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 9,599 Flonase allergy relief users. Check the latest studies of Flonase allergy relief.



On Jul, 15, 2026

89 people who take Fluoxetine hydrochloride and Flonase allergy relief together, and have interactions are studied.

Fluoxetine hydrochloride and Flonase allergy relief drug interactions.

What are the common drug interactions of Fluoxetine Hydrochloride and Flonase Allergy Relief, by gender? *:

female:

  1. Therapeutic response decreased (less preventive response)
  2. Thyroid mass
  3. Weight increased
  4. Abdominal discomfort
  5. Headache (pain in head)
  6. Infection
  7. Nausea (feeling of having an urge to vomit)
  8. Infusion site pain
  9. Infusion site swelling
  10. Chest pain

male:

  1. Arteriosclerosis (thickening and hardening of arteries)
  2. Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
  3. Abnormal behaviour
  4. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  5. Catatonia (unresponsive to external stimuli)
  6. Dizziness
  7. Erythema of eyelid (redness of the eyelid)
  8. Eye pain
  9. Eyelid pain
  10. Hand dermatitis (hand infection of skin)

What are the common drug interactions of Fluoxetine Hydrochloride and Flonase Allergy Relief, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Death

20-29:

  1. Memory impairment
  2. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  3. Panic disorder
  4. Suicidal ideation
  5. Nausea (feeling of having an urge to vomit)
  6. Abdominal discomfort
  7. Allergy to animal
  8. Allergy to plants
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness)
  10. Malaise (a feeling of general discomfort or uneasiness)

30-39:

  1. Pain
  2. Premenstrual dysphoric disorder
  3. Restless legs syndrome (a powerful urge to move your legs)
  4. Suicidal ideation

40-49:

  1. Infusion site rash
  2. Infusion site reaction
  3. Infusion site swelling
  4. Injection site mass
  5. Injection site pain
  6. Injection site reaction
  7. Insomnia (sleeplessness)
  8. Lethargy (tiredness)
  9. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  10. Night sweats (sweating in night)

50-59:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Pruritus (severe itching of the skin)
  3. Ankle fracture
  4. Dry mouth
  5. Dry skin
  6. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  7. Eye pain
  8. Hysterectomy
  9. Neuralgia (pain in one or more nerves)
  10. Photophobia (extreme sensitivity to light)

60+:

  1. Fall
  2. Ataxia (loss of full control of bodily movements)
  3. Infusion site mass
  4. Infusion site pain
  5. Infusion site swelling
  6. Injection site bruising
  7. Neuropathy peripheral (surface nerve damage)
  8. Pain in jaw
  9. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  10. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 28 people, 31.46%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 25 people, 28.09%
  3. Drowsiness: 16 people, 17.98%
  4. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 11 people, 12.36%
  5. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 10.11%
  6. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 8 people, 8.99%
  7. Immunodeficiency Common Variable: 7 people, 7.87%
  8. Primary Immunodeficiency Syndrome: 6 people, 6.74%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 5 people, 5.62%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fluoxetine hydrochloride and Flonase allergy relief:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluoxetine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flonase allergy relief:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fluoxetine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flonase allergy relief and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride and fluticasone propionate (the active ingredients of Fluoxetine hydrochloride and Flonase allergy relief, respectively), and Fluoxetine hydrochloride and Flonase allergy relief (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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