Fosamax and Valcyte drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fosamax (alendronate sodium) and Valcyte (valganciclovir hydrochloride). Common drug interactions include sinusitis among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Fosamax and Valcyte. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Fosamax?

Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 105,452 Fosamax users. Check the latest studies of Fosamax.

What is Valcyte?

Valcyte has active ingredients of valganciclovir hydrochloride. It is often used in cmv - immunocompromised host. eHealthMe is studying from 6,409 Valcyte users. Check the latest studies of Valcyte.

On Jul, 04, 2026

76 people who take Fosamax and Valcyte together, and have interactions are studied.

What are the common drug interactions of Fosamax and Valcyte, by gender? *:

female:

Sinusitis (inflammation of sinus)
Renal failure (kidney dysfunction)
Erythema (redness of the skin)
Gait disturbance
Joint range of motion decreased (disease of joint movement)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pruritus generalised (generalized itching)
Skin discolouration (change of skin colour)
Skin exfoliation (removal of the oldest dead skin cells)
Skin hyperpigmentation (disorders affect the colour of your skin)

male:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Complications of transplanted kidney
Decreased appetite
Respiratory syncytial virus infection (viral disease of respiratory system)
Asthenia (weakness)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Fatigue (feeling of tiredness)
Hypokalaemia (low potassium)
Insomnia (sleeplessness)

What are the common drug interactions of Fosamax and Valcyte, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Complications of transplanted kidney
Diarrhoea
Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hyperkalaemia (damage to or disease of the kidney)
Hypokalaemia (low potassium)
Intra-abdominal haematoma (intra-abdominal localized swelling filled with blood)
Kidney fibrosis (excess fibrous connective tissue in kidney)
Lymphocele (a collection of lymphatic fluid within the body not bordered by epithelial lining)
Renal tubular atrophy (wasting of kidney tubules)

30-39:

Blood cholesterol increased
Abdominal pain upper
Alcohol use
Arrhythmia (irregular heartbeat)
Blood thyroid stimulating hormone increased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Contusion (a type of hematoma of tissue in which capillaries)
Cytomegalovirus test positive
Deafness unilateral

40-49:

Blood amylase increased
Cytomegalovirus antibody positive
Leukopenia (less number of white blood cells in blood)
Myalgia (muscle pain)
Neutropenia (an abnormally low number of neutrophils)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pain
Pancreas transplant rejection
Pathogen resistance
Staphylococcal infection (an infection with staphylococcus bacteria)

50-59:

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Pruritus generalised (generalized itching)
Skin discolouration (change of skin colour)
Skin exfoliation (removal of the oldest dead skin cells)
Skin hyperpigmentation (disorders affect the colour of your skin)
Skin hypertrophy (skin cells enlarges)
Skin induration (an abnormally hard spot or area on the skin)
Skin tightness

60+:

Nausea (feeling of having an urge to vomit)
Blood creatinine increased
Insomnia (sleeplessness)
Pancreatitis (inflammation of pancreas)
Renal tubular necrosis (death of kidney tubules)
Vomiting
Renal failure (kidney dysfunction)
Arrhythmia (irregular heartbeat)
Blood thyroid stimulating hormone increased
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

What are the existing conditions these people have? *

Pain: 10 people, 13.16%
High Blood Pressure: 6 people, 7.89%
Constipation: 6 people, 7.89%
Immunodeficiency Disorders: 5 people, 6.58%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 5 people, 6.58%
High Blood Cholesterol: 4 people, 5.26%
Diabetes: 4 people, 5.26%
Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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