Furosemide and Lotronex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Furosemide (furosemide) and Lotronex (alosetron hydrochloride). Common drug interactions include polyp among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Furosemide and Lotronex. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Furosemide?

Furosemide has active ingredients of furosemide. It is often used in fluid retention. eHealthMe is studying from 316,095 Furosemide users. Check the latest studies of Furosemide.

What is Lotronex?

Lotronex has active ingredients of alosetron hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 6,841 Lotronex users. Check the latest studies of Lotronex.



On Jul, 08, 2026

27 people who take Furosemide and Lotronex together, and have interactions are studied.

Furosemide and Lotronex drug interactions.

What are the common drug interactions of Furosemide and Lotronex, by gender? *:

female:

  1. Polyp
  2. Rectal haemorrhage (bleeding from anus)
  3. Renal failure (kidney dysfunction)
  4. Respiratory failure (excl neonatal) (inadequate gas exchange by the respiratory system(excluding neonatal))
  5. Retching (strong involuntary effort to vomit)
  6. Rhinorrhoea (watery mucus discharge from the nose)
  7. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  8. Upper limb fracture
  9. Vaginosis fungal (inflammation of the vagina caused by fungal infection)
  10. Vascular rupture

male:

  1. Abdominal pain
  2. Abdominal pain lower
  3. Constipation
  4. Diarrhoea
  5. Foot ulcer
  6. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  7. Heart rate increased
  8. Heart rate irregular
  9. Injury
  10. Lymphoid tissue hyperplasia (a rapid increase in the number of normal cells (called lymphocytes) that are contained in lymph nodes)

What are the common drug interactions of Furosemide and Lotronex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  2. Essential hypertension (primary hypertension)
  3. Gastritis (inflammation of stomach)
  4. Gastro-oesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Gout (uric acid crystals building up in the body)
  7. Intestinal obstruction
  8. Joint sprain (an injury to joint surrounding flexible fibres)
  9. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Diarrhoea
  2. Abdominal pain
  3. Constipation
  4. Faecal impaction
  5. Staphylococcal infection (an infection with staphylococcus bacteria)
  6. Vomiting
  7. Abdominal pain lower
  8. Abdominal pain upper
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Anxiety

60+:

  1. Constipation
  2. Abdominal pain
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Urinary tract infection
  5. Abdominal abscess (collection of pus in abdomen)
  6. Acute abdomen
  7. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  8. Arrhythmia (irregular heartbeat)
  9. Ascites (accumulation of fluid in the abdominal cavity)
  10. Atelectasis (partial or complete collapse of the lung)

What are the existing conditions these people have? *

  1. Infection: 2 people, 7.41%
  2. Hypersensitivity: 2 people, 7.41%
  3. High Blood Pressure: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Furosemide and Lotronex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Furosemide and Lotronex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Furosemide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lotronex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Furosemide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lotronex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on furosemide and alosetron hydrochloride (the active ingredients of Furosemide and Lotronex, respectively), and Furosemide and Lotronex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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