Gabapentin and Osmolex er drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gabapentin (gabapentin) and Osmolex er (amantadine hydrochloride). Common drug interactions include tremor among females and hallucination among males.
The phase IV clinical study analyzes what interactions people have when they take Gabapentin and Osmolex er. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Gabapentin?
Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 322,983 Gabapentin users. Check the latest studies of Gabapentin.
What is Osmolex er?
Osmolex er has active ingredients of amantadine hydrochloride. eHealthMe is studying from 783 Osmolex er users. Check the latest studies of Osmolex er.
36 people who take Gabapentin and Osmolex er together, and have interactions are studied.

What are the common drug interactions of Gabapentin and Osmolex Er, by gender? *:
female:
- Tremor (trembling or shaking movements in one or more parts of your body)
- Weight decreased
- Dysphagia (a condition in which swallowing is difficult or painful)
- Hypophagia (reduced food intake)
- Dizziness
- Drug ineffective
- Gait disturbance
- Lip blister
- Memory impairment
- Petit mal epilepsy (absence seizure)
male:
- Hallucination (an experience involving the perception of something not present)
- Death
- Urinary incontinence (inability to control the flow of urine and involuntary urination)
- Urinary tract infection
- Balance disorder
- Blood pressure increased
- Dyspnoea (difficult or laboured respiration)
- Muscular weakness (muscle weakness)
- Road traffic accident
- Dizziness
What are the common drug interactions of Gabapentin and Osmolex Er, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Memory impairment
- Petit mal epilepsy (absence seizure)
- Speech disorder
60+:
- Tremor (trembling or shaking movements in one or more parts of your body)
- Dizziness
- Diarrhoea
- Drug ineffective
- Gait disturbance
- Lip blister
- Pruritus generalised (generalized itching)
- Rash
- Urinary incontinence (inability to control the flow of urine and involuntary urination)
- Balance disorder
What are the existing conditions these people have? *
- Parkinson's Disease: 27 people, 75.00%
- Dyskinesia (abnormality or impairment of voluntary movement): 7 people, 19.44%
- Sleep Disorder: 3 people, 8.33%
- Neuropathy Peripheral (surface nerve damage): 3 people, 8.33%
- Hallucinations (sensations that appear real but are created by your mind): 3 people, 8.33%
- Depression: 3 people, 8.33%
- Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 5.56%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 5.56%
- High Blood Pressure: 2 people, 5.56%
- High Blood Cholesterol: 2 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Gabapentin and Osmolex er?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Gabapentin (322,983 reports)
- Osmolex er (783 reports)
Browse all drug interactions of Gabapentin and Osmolex er:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gabapentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Osmolex er:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gabapentin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Osmolex er and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Yang Y, Teja S, Baig K, "Bilateral corneal edema associated with amantadine", Canadian Medical Association Journal, 2015 Oct .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
- Cattoni J, Parekh R, "Acute respiratory distress syndrome: A rare presentation of amantadine toxicity", The American journal of case reports, 2012 Jan .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Yang Y, Teja S, Baig K, "Bilateral corneal edema associated with amantadine", Canadian Medical Association Journal, 2015 Oct .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
- Cattoni J, Parekh R, "Acute respiratory distress syndrome: A rare presentation of amantadine toxicity", The American journal of case reports, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on gabapentin and amantadine hydrochloride (the active ingredients of Gabapentin and Osmolex er, respectively), and Gabapentin and Osmolex er (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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