Gardasil and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gardasil (human papillomavirus vaccine) and Acetaminophen (acetaminophen). Common drug interactions include nausea among females and bone density decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Gardasil and Acetaminophen. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Gardasil?

Gardasil has active ingredients of human papillomavirus vaccine. eHealthMe is studying from 489 Gardasil users. Check the latest studies of Gardasil.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 09, 2026

13 people who take Gardasil and Acetaminophen together, and have interactions are studied.

Gardasil and Acetaminophen drug interactions.

What are the common drug interactions of Gardasil and Acetaminophen, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Osteochondritis (a painful type of osteochondritis where the cartilage or bone in a joint is inflamed)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Viral infection
Vomiting
Conjunctivitis infective (infection of the conjunctiva)
Corneal neovascularisation (excessive ingrowths of blood vessels into the cornea)
Corneal opacity (scarring or clouding of the cornea)
Keratitis interstitial (corneal scarring due to chronic inflammation)
Lymphadenopathy (disease or enlargement of lymph nodes)

male:

Bone density decreased
Bone loss
Injury
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)

What are the common drug interactions of Gardasil and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Ear infection
Hilar lymphadenopathy (disease of the lymph nodes due to infection)
Hodgkin's disease (cancer originating from white blood cells)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Mycoplasma infection (bacterial infection)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Osteochondritis (a painful type of osteochondritis where the cartilage or bone in a joint is inflamed)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Photophobia (extreme sensitivity to light)

10-19:

Throat irritation
Conjunctivitis infective (infection of the conjunctiva)
Corneal neovascularisation (excessive ingrowths of blood vessels into the cornea)
Corneal opacity (scarring or clouding of the cornea)
Dysmenorrhoea (painful menstruation)
Ear infection
Hilar lymphadenopathy (disease of the lymph nodes due to infection)
Hodgkin's disease (cancer originating from white blood cells)
Hypersensitivity
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

20-29:

Bone density decreased
Bone loss
Injury
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)

30-39:

Asthenia (weakness)
Blood pressure decreased
Arrhythmia (irregular heartbeat)
Blood bilirubin unconjugated increased
Confusional state
Diastolic hypertension
Drug intolerance (drug sensitivity)
Memory impairment
Microalbuminuria (albumin into the urine)
Petechiae (a small red or purple spot caused by bleeding into the skin)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 5 people, 38.46%
Birth Control: 3 people, 23.08%
Multiple Allergies (allergy to multiple agents): 2 people, 15.38%
Headache (pain in head): 2 people, 15.38%
Duodenitis (inflammation of the duodenum): 2 people, 15.38%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 15.38%
Cough: 2 people, 15.38%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 15.38%
Sleep Disorder: 1 person, 7.69%
Premenstrual Syndrome: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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